Poly(Ethylene Glycol) 聚乙二醇
CAS 25322-68-3 MFCD00081839
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Alphabetic, Analytical Standards, Analytical/Chromatography, Application CRMs, Certified Reference Materials (CRMs),
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Emulsifiers, Thickeners, Opacifiers, Essential Chemicals, Inorganic Salts, Solutions and Reagents,
- {SNA} Core Bioreagents,
- {SNA} Ess
产品应用
- Usually used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.
相关文献及参考
- Catalyzes the reaction of potassium aryloxides with dichloromethane at room temperature to give good yields of diaryloxymethanes: J. Chem. Res. (Synop.), 503 (1995).
- Merck: 14,7568
安全信息
GHS Symbol
- H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H302 Harmful if swallowed 吞食有害
- H311 Toxic in contact with skin 皮肤接触中毒
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P273 Avoid release to the environment. 避免释放到环境中。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312+P330
- P302+P352+P312
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R33 Danger of cumulative effects 有累积作用的危险
- R52/53
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 8 gm/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,293,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 34 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,3847,1982
TYPE OF TEST : LD50 - Lethal
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 36 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,3847,1982
TYPE OF TEST : LD50 - Lethal dose
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 50900 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes REFERENCE : ARZNAD Arzneimittel-Forschung.
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 416 mg/kg/Y-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - other reproductive system tumors REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 15,252,1961
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Cells - not otherwise specified DOSE/DURATION : 50 pph REFERENCE : DKBSAS Doklady Biological Sciences (English Translation). Translation of DANKAS: Biological Section. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.112- 1957- Volume(issue)/page/year: 240,228,1978
TYPE OF TEST : DNA damage TEST SYSTEM : Microorganism - not otherwise specified DOSE/DURATION : 100 gm/L REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 72,4288,1975
其他信息
- 聚氧乙烯(PEO)是一种水溶性的聚氧乙烯树脂。
- 有轻微特殊气味。微有吸湿性。遇热易熔化。溶于水和乙醇
- 聚氧化乙烯(PEO)是一种水溶性树脂。相对分子质量200~20000的产品被称为聚乙二醇(PEG),它们是粘性液体或蜡状固体:分子相对质量大于1x105的产品被称为聚氧化乙烯,PEO聚氧化乙烯是白色可流动粉末,分子结构为(CH2CH2O),此类树脂活性端基的浓度较低,没有明显的端基活性。