CAS 64-19-7 MFCD00036152-Acetic Acid Glacial 乙酸(易涉毒) TAO{mole}

Acetic Acid Glacial 乙酸(易涉毒)

CAS 64-19-7 MFCD00036152

化学结构图

SMILES: CC(=O)O

化学属性

Mol. Formula	CH3CO2H
Mol. Weight	60
Refractive index	n20/D 1.371(lit.)
Boiling Point	117-118
Density	1.048
Melting Point	16-17
Flash Point	41°C(lit.)
TSCA	Yes
Autoignition Point	800 °F
Vapor Density	2.07 (vs air)
Vapor Pressure	15.2 hPa ( 20.0 °C)
Solubility	Soluble in water, ethanol, ether, glycerol, most organic solvents, and carbon tetrachloride. Insoluble in carbon disulfide.
Stability	对湿度敏感
Danger-Level	乙类

别名和识别编码

Chemical Name	Acetic Acid Glacial
Synonym	Acetic acid, glacial Azijnzuur Essigsaeure Glacial acetic acid Octowy kwas Vinegar acid 乙酸乙酸溶液乙酸添加剂冰醋酸;乙酸醋酸36%
CAS Number	64-19-7
PubChem Substance ID	176
EC Number	200-580-7
Beilstein Registry Number	2(4)94
MDL Number	MFCD00036152
Merck Number	55
Chemical Name Translation	乙酸(易涉毒)
InChIKey	QTBSBXVTEAMEQO-UHFFFAOYSA-N
Reaxys-RN	506007
Wiswesser Line Notation	QV1
LabNetwork Molecule ID	LN00162861
InChI	InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

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品牌质保精细包装现货库存一流品牌服务

产品应用

常用有机酸。分析、溶剂、有机合成，制备缓冲液等。

安全信息

GHS Symbol

WGK Germany1

Hazard Codes 8 C

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment Faceshields, Gloves, Goggles Eyeshields, Gloves Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSAF1225000

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P233 Keep container tightly closed. ?保持容器密闭。
P234 Keep only in original container. 只保留在原来的容器中。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P241+P242+P243
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P330+P331+P310
P302+P352
P303+P361+P353
P303+P361+P353+P310+P363
P304+P340
P304+P340+P310
P305+P351+P338
P305+P351+P338+P310
P309+P311
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
P403+P235
P405 Store locked up. 上锁保管。
P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

UN Number 2789 UN2789

Risk Statements

R10 Flammable 易燃
R34 Causes burns 会导致灼伤
R35 Causes severe burns 会导致严重灼伤

Safety Statements

S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Packing GroupII

Storage condition 密封，在16℃以上的暖处保存，以防凝固而致使容器破裂室温储存充氩保存

Hazard Class8/3

Warnings 危化品目录(2015)

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Rectal
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 281 uL/kg
TOXIC EFFECTS :
   Gastrointestinal - alteration in gastric secretion
   Liver - liver function tests impaired
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   JTCTDW Journal of Toxicology, Clinical Toxicology.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.19-    1982-  Volume(issue)/page/year:
   82,333,1994

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent -

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3310 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMDJAP Delaware State Medical Journal.  (Wilmington, DE)  V.1-32(1),
   1929-60.  For publisher information, see DSMJAA.  Volume(issue)/page/year:
   31,276,1959

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5620 ppm/1H
TOXIC EFFECTS :
   Sense

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   18,141,1961

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       :

TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 79279 ug/kg
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   55,983,1975

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 240,195,1990

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 279,75,1992

{hazar

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm/24H
REFERENCE :
   THAGA6 Theoretical & Applied Genetics.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.38-    1968-
   Volume(issue)/page/year: 39,330,1969

TYPE OF TEST

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTE

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1201 mg/kg
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   55,983,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 400 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   FESTAS Fertility and Sterility.  (American Fertility Soc., 608 13th Ave. S,
   Birmingham, AL 35282) V.1-    1950-  Volume(issue)/page/year: 24,884,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 700 mg/kg
SEX/DURATION            : lactating female 18 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   NTOTDY Neurobehavioral Toxicology and Teratology.  (Fayetteville, NY) V.3-8,
   1981-86.  For publisher information, see NETEEC. Volume(issue)/page/year:
   4,105,1982

Restrict 危险品

其他信息

1.将本品垂直放于1升的容量瓶上。
Acetic acid is used in biochemical and molecular biological as a buffer when combined with sodium acetate in a specific buffering range fo pH 3.6 - 5.6. Acetic acid also is used in organic synthesis for the production of different acetates and acetyl compounds and as a precursor of polyvinylacetate and cellulose acetate.
每瓶安瓿可稀释成一升的滴定液
具有刺激性特殊气味，有腐蚀性。
2.用附带的小工具从上至下刺破薄膜，使浓缩液流入容量瓶中
使用方法：
有刺激性气味。有腐蚀性，对皮肤有刺激痛，发水泡。其蒸气有毒，并易着火。纯的无水乙酸（冰醋酸）是无色的吸湿性液体，凝固点为16.7℃（62℉），凝固后为无色晶体。能与水、乙醇、乙醚、四氯化碳和甘油混和，难溶于二硫化碳。凝固时体积微缩。
注：本包装为浓缩液，是用来稀释成1升的分析滴定液。稀释后的浓度即为标签上所示浓度。（在允许的不确定度区间之内）
3.取适量的蒸馏水润洗本产品的容器，并使之流入到容量瓶中，直至加到一升容量瓶的刻度处