CAS 62-56-6 MFCD00008067-Thiourea 硫脲 TAO{mole}

Thiourea 硫脲

CAS 62-56-6 MFCD00008067

化学结构图

SMILES: NC(N)=S

化学属性

Mol. Formula	CH4N2S
Mol. Weight	76.12
Melting Point	170-176
Density	1.405
TSCA	Yes
Solubility	13.6 G/100 ML (20 ºC)
Stability	对空气敏感

别名和识别编码

Chemical Name	Thiourea
Synonym	Thiourea {} {} {} { {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} epapesticidechemicalcode080201 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {Chemicalbook} beta-Thiopseudourea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} Usaf ek-497 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {hazard_com} USAF EK-497 {} {} {} {} {} {} {} {}
CAS Number	62-56-6
PubChem Substance ID	2723790
EC Number	200-543-5
Beilstein Registry Number	605327
MDL Number	MFCD00008067
Reaxys-RN	605327
Merck Number	9367
Chemical Name Translation	硫脲
Wiswesser Line Notation	ZYZUS
LabNetwork Molecule ID	LN00193919
InChI	InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
Canonical SMILES	NC(N)=S

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

还原剂。铅、铊、镉的沉淀剂。检定和测定铋、饿、钌、硒、铅、碲、钯和亚硒酸盐。有机合成，由卤烷制备硫醇。

安全信息

GHS Symbol

WGK Germany3

Hazard statements

H301 Toxic if swallowed 吞食有毒
H351 Suspected of causing cancer 怀疑致癌
H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
H302 Harmful if swallowed 吞食有害
H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes

RTECSYU2800000

Precautionary statements

P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P302+P350
P337+P313
P308+P313
P403+P233
P273 Avoid release to the environment. 避免释放到环境中。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P201 Obtain special instructions before use. 使用前获取专门指示。
P302+P352+P333+P313+P362+P364
P304+P340
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P304+P340+P312
P305+P351+P338+P337+P313
P301+P310+P330
P405 Store locked up. 上锁保管。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。

Signal word

Safety Statements

S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R51/53
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
R22 Harmful if swallowed 吞咽有害
R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

UN Number UN3077 3077

Packing GroupIII

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} { {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {}

Hazard Class6.1

Warnings 危化品目录(2015)

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 78 gm/kg/56W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Eye) - tumors
   Sense Organs and Special Senses (Ear) - effect, not otherwise specified
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   17,302,1957

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   108,626,1948

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Multiple routes
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 151 gm/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Eye) - tumors
   Sense Organs and Special Senses (Ear) - effect, not otherwise specified
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, P

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   108,626,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 30(3),42,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 147 mg/kg
TOXIC EFFECTS :
   Details

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 5,177,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 436 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 3,597,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springf

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 329 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 272,145,1992

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 100 mg/L
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 67,1303,1981

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 20 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 79,1171,1982

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   42,3010,1982

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 60 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Neth

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 140 mmol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 13,2389,1992

TYPE OF TE

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 gm/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 23,335,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4800 mg/kg
SEX/DURATION            : female 17-22 day(s) after conception
                          lactating female 10 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 31,57A,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 240 mg/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 13,263,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent -

Restrict 危险品

其他信息

急性毒性:口服-大鼠 LD50: 125 毫克/公斤; 腹腔-小鼠 LD50: 100 毫克/公斤
硫脲价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 10022318 硫脲;硫代尿素 500g 24.8元 2011/08/23 10022328 硫脲;硫代尿素 500g 23元 2010/06/21 138915000 硫脲 Thiourea 99%, extra pure 500 GR 402元
用途五:本品用以合成磺胺噻唑、蛋氨酸和肥猪片等药物的原料。用作染料及染色助剂、树脂及压塑粉的原料。也可用作橡胶的硫化促进剂、金属矿物的浮选剂、制邻苯二甲酸酐和富马酸的催化剂，以及用作金属防锈蚀剂。在照相材料
Sigma Aldrich:62-5
可燃性危险特性:受热放出有毒氧化硫和氧化氮气体
方法一:合成法用硫化钡与盐酸(或硫酸)反应，用石灰乳负压吸收，再与石灰氮反应，经过滤、冷却结晶、离心分离、干燥，
{Chemica
用途一:用于制造磺胺药物、染料、树脂、压塑粉等，也用作橡胶的硫化促进剂、金属矿物的浮选剂等
方法三:用石灰乳在负压、冷却下吸收硫化氢，生成硫氢化钙溶液。将硫氢化钙与氰氨化钙（石灰氮）按1：5摩尔比，于80℃左右反应3h，即得硫脲溶液，过滤、浓缩、冷却结晶、甩滤干燥，得成品硫脲。此外，用硫氰酸铵法和重氮甲烷法也可制得。
刺激数据:眼睛-兔子 14% 中度
{Chem
图谱信息:硫脲(62-56-6)质谱(MS) 硫脲(62-56-6)红外图谱(IR2) 硫脲(62-56-6)红外图谱(IR1)
方法二:其制备方法是以硫化钡与硫酸或盐酸反应，硫化氢气体经石灰乳负压吸收制得硫化
类别:有毒物品
Acros Organics:硫脲 Thiourea, extra pure, 99%(62-56-6)
下游产品:去甲氨噻肟酸乙酯 --> 奥吩达唑 --> 哌唑嗪 --> 2-乙硫基-4-氨基嘧啶-5-羧酸乙酯 --> 4-(4-氯苯基)嘧啶-2-巯基 --> 2-氨基-6-甲基嘧啶-4-硫醇 --> 2-氨基-Α-((1-羧基-1-甲基乙氧)亚氨基)-4-噻唑乙酸 --> 9,10-二甲基蒽 --> 环己硫醇 --> 2-(乙硫基)-4-羟基嘧啶-5-乙酸乙酯 --> 4-羟基-6-巯基吡唑(3,4-D)嘧啶 --> 2-甲硫基-4,6-二甲基嘧啶 --> 5-乙基-2-硫脲嘧啶 --> 2-氨基-4-苯基-5-噻唑甲酸乙酯 --> 十二硫醇 --> 5-甲氧基-2-巯基-4-嘧啶醇 --> 5-乙酰基-2-氨基-4-甲基噻唑 --> 4,6-二氨基-2-巰基嘧啶 --> 2-氨基-4-甲基噻唑-5-羧酸乙酯 --> N-乙酰硫脲 --> 4,6-二羟基-2-巯基嘧啶 --> 1-辛硫醇 --> 2-巯基-4-氨基嘧啶-5-腈 --> 乙酸胍 --> 2-氨基噻唑-4-乙酸 --> 异丁硫醇 --> 2-氨基-2-噻唑啉盐酸盐 --> 4-氨基-6-羟基-2-巯基嘧啶一水物 --> 氨噻肟酸 --> 2-氯噻唑-4-羧酸甲酯 --> 二硫氰基甲烷 --> 硫尿嘧啶 --> 噻唑 --> 2-氨基-5-甲基噻唑
海关编码:29309070
上游原料:盐酸 --> 硫酸 --> 氢硫酸 --> 硫氰酸铵 --> 硫酸钡 --> 氰氨化钙 --> 硫化钡 --> 亚硝酸乙酯 --> 重
常规方法:本品用内衬聚乙烯塑料袋的编织袋包装，每袋净重（25±0.2）kg。应贮存在阴凉通风干燥处，在贮运和装卸中应防潮。
MOL 文件:62-56-6.mol
方法一:合成法用硫化钡与盐酸(或硫酸)反应，用石灰乳负压吸收，再与石灰氮反应，经过滤、冷却结晶、离心分离、干燥，制得硫脲成品。其 BaS+2HCl→BaC12+H2S↑ CaO+H2O→Ca(OH)2 Ca(OH)2+2H2S→Ca(SH)2+2H2O 2CaCN2+Ca(SH)2+6H2O→2(NH2)2CS+3Ca(OH)2
{Chemicalbook