Phenolphthalein 酚酞

CAS 77-09-8 MFCD00005913

化学结构图

77-09-8
SMILES: O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

化学属性

Mol. FormulaC20H14O4
Mol. Weight318.32
Melting Point261-263
TSCAYes
Density1.299
SolubilitySoluble in alcohol. Slightly soluble in ether
Flash Point11°(52°F)
Appearance 白色粉末。熔点258-262℃,相对密度1.27。溶于10份醇,溶于稀碱溶液呈深红色,微溶于醚,不溶于水,无臭,无味。
Stability对湿度敏感
Boiling Point82 °C(lit.)
Refractive indexn20/D 1.377(lit.)

别名和识别编码

Chemical NamePhenolphthalein
Synonym Phenolphthalein {LY} Phenolphthalein {} {LY} Phenolphthalein {} {} {LY} Phenolphthalein {} {} {} {LY} Phenolphthalein {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenolphthalein {} {} {} {} {} {} {}
MDL NumberMFCD00005913
CAS Number77-09-8
PubChem Substance ID4764
EC Number201-004-7
Beilstein Registry Number18(3/4)1945
Merck Number7243
Reaxys-RN284423
Chemical Name Translation酚酞
InChIKeyKJFMBFZCATUALV-UHFFFAOYSA-N
Wiswesser Line NotationT56 BVO DHJ D- D-/R DQ 2
LabNetwork Molecule IDLN00195715
InChIInChI=1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H
Canonical SMILESO=C1OC(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)C4=C1C=CC=C4
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Analytical Reagents, Analytical/Chromatography, Indicators, Titration, pH Indicators - Solids
  • {SNA} Indicators, Titration, pH Indicators - Solids, 分析/色谱, 分析试剂
  • {SNA} Indica
  • {SNA} Indicator Solutions, Indicators, Titration, 分析/色谱, 分析试剂
  • {SNA} Core Bioreagents, Indicators, P, Research Essentials,
  • {SA} Analytical Reagents, Analytical/Chromatography, Indicator Solutions, Indicators, Titration
  • {SNA} Core Bioreagents, Indicators, P, Research Essentials, Stains & Dyes, A to Z,
  • {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; alicycle; large ring; fused rings; 5ring; 6ring; 9ring; ester; lactone; alcohol; 1fragment

产品应用

  • 酸碱指示剂, 非水溶液滴定指示剂, 色谱分析试剂。

相关文献及参考

  • Merck: 14,7243 Beilstein: 18,V,4,188
  • Short: EINECS
  • Short: IV/8A
  • Acid-base indicator: pH 8.0 - 10.0.
  • Merck: 14,7243

安全信息

GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P303+P361+P353
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P308+
  • P308+P313
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P337+P313
  • P370+P378
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H301+H311+H331
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H350 May cause cancer 可能致癌
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H370 Causes damage to organs 导致器官损伤
WGK Germany3
Signal word Danger
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Gloves
RTECSSM8380000
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭,置于通风良好的场所;
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Packing GroupIII
UN Number 1993 UN1987 UN1986 1170 UN 1219 3/PG 2 UN 1993
Risk Statements
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
  • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
  • R45 May cause cancer 可能致癌
  • R10 Flammable 易燃
  • R22 Harmful if swallowed 吞咽有害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
Hazard Codes F F,T Xn Xi,F,Xn T Xn,T,F
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light Flammables area {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, pr
Hazard Class3
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 281 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Endocrine - tumors
   Skin and Appendages - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-465,1996

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 364 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
   Endocrine - adrenal cortex tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-465,1996

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,25,1953

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,30,1953

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Gastrointestinal - nausea or vomiting
   Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
   PGMJAO Postgraduate Medical Journal.  (Blackwell Scientific Pub. Ltd., POB
   88, Oxford, UK) V.1-    1925-  Volume(issue)/page/year: 60,491,1984

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1680 mg/kg/14D (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 341,151,1995

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 50 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 341,151,1995

其他信息

  • 灭火剂:干粉、干砂、二氧化碳、泡沫
  • 上游原料:磷酸 --> 硅藻土 --> 丙烯 --> 2-氨基-3-氯苯甲酸 --> 丙酯 --> 循环压缩机
  • 图谱信息:酚酞(77-09-8)红外图谱(IR1) 酚酞(77-09-8)红外图谱(IR2) 酚酞(77-09-8)核磁图( 13 CNMR) 酚酞(77-09-8)Raman光谱 酚酞(77-09-8)质谱(MS) 酚酞(77-09-8)核磁图( 1 HNMR)
  • 使用限量:FEMA(mg/kg):软饮料25,糖果10~75,焙烤食品75。
  • MOL 文件:67-63-0.mol
  • 所属类别二:食品添加剂: 食品加工助剂: 溶剂和助溶剂
  • FEMA:2929
  • 防护措施:易燃低毒物质。蒸气的毒性为乙醇的二倍,内服时的毒性则相反。高浓度蒸气具有明显麻醉作用,对眼、呼吸道的粘膜有刺激作用,能损伤视网膜及视神经。大鼠经口LD50为5.47g/kg。空气中最高容许浓度980mg/m3。操作人员应戴防毒面具。浓度高时应戴气密式防护眼镜。密闭设备及管路;实行局部或全面通风。
  • 蒸气密度:2.1 (vs air)
  • 用途三:异丙醇是农药生产的重要中间体,可以生产杀菌剂稻瘟灵、异稻瘟净等,杀虫杀螨剂胺丙畏、水胺硫磷
  • 危害:经常暴露于异丙醇的人存在一定的中毒风险,试验分析员,打字员,画家,木匠和内务人员,以及使用异丙醇的不同行业工人属于职业暴露人群。 口服,吸入,皮肤和眼睛是受其影响的四个最基本途径。偶然摄入异丙醇二十毫升以上可能导致毒性发作。周围环境超过500ppm浓度水平,应该使用自给式呼吸器。当浓度达到12000,就会及其危险,甚至危及健康和生命。尽管通过皮肤吸收的很少,但是长期接触也会造成不良反应,过度暴露可以导致眼,鼻,喉不适。它也可能会导致中枢神经系统衰弱。严重情况下,会引起混乱,精神协调,循环系统和呼吸系统问题。 若发现吸入异丙醇之病患,应先移除污染源或将患者移到新鲜空气处。倘若患者停止呼吸应立即施予人工呼吸后再就医。 若发现误食异丙醇者,应先给病患服用大量的水后再送医治疗。 异丙醇排放物还会污染环境,异丙醇是一种光化学氧化剂,它与存在地面附近的其它痕量气体一样,受阳光照射会形成臭氧,从而导致所谓“夏季烟雾”现象,光化学烟雾会刺激人的眼睛和呼吸系统,危害人们的身体健康和植物的生长,因此,异丙醇是一种对环境、
  • 不同用途的市场需求分析:欧洲溶剂工业集团(ESIG)称,2001年欧洲中间体需求占到异丙醇消费量的32%,有14%的异丙醇用作防冰剂,13%用于油漆和
  • 酚酞价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 10015318 酚;石炭酸; 苯酚 500g 26元 2011/08/23 1001
  • 蒸气压:33 mm Hg ( 20 °C)
  • 作用与用途:异丙醇是重要的化工产品和原料。主要用于制药、化妆品、塑料、香料、涂料及电子工业上用作脱水剂及清洗剂。测定钡、钙、镁、镍、钾、钠和锶等的试剂。色谱分析参比物质。 在电路板制造业,它被用作清洗剂,以及制作PCB孔导电。很多人发现它不但可以很好的清洗主板,而且往往可以取得最佳的效果。此外,它还用于其他电子设备,包括清洁光盘盒,软盘驱动器,磁带,以及CD或DVD播放机光盘驱动器的激光头等。 异丙醇还可以作为溶剂用于柔印,平版印刷,凹版印刷,并作为设备清洁剂。在油墨中也经常包含这种成分。它还是实验室稀释和提取的重要溶剂。此外,异丙醇还用作汽油添加剂和燃料管道的除冰剂。 在制药和化妆品工业,异丙醇用于制造生产擦洗液,手和身体乳液,防腐剂,以及制药发红剂。它也用于油漆,稀释剂,涂料,清洁剂和抛光,以及表面杀菌,医院消毒,食品加工厂等。 在许多工业和消费产品中,异丙醇用作低成本溶剂,也用作萃取剂,在许多情况下可代替乙醇使用。 异丙醇还用作油品
  • 方法二:由硫酸吸收丙烯,再水解后精馏而得纯品。
  • 用途二:用作实验用化学试剂及色谱分析试剂
  • 刺激数据:眼睛- 兔子 100 毫克/ 24小时 中度
  • 凝固点:-89.5℃
  • 在空

系列性分类


相关产品推荐