CAS 96-09-3 MFCD00005121-Styrene Oxide 氧化苯乙烯 TAO{mole}

Styrene Oxide 氧化苯乙烯

CAS 96-09-3 MFCD00005121

化学结构图

SMILES: C1CCC(C2CO2)CC1

化学属性

Mol. Formula	C8H8O
Mol. Weight	120
Refractive index	1.5340 to 1.5360
Boiling Point	194
Density	1.054
Melting Point	-37
Flash Point	77°C(lit.)
TSCA	Yes
Autoignition Point	928 °F
Vapor Density	4.14 (vs air)
Vapor Pressure	<;1 mmHg ( 20 °C)
Solubility	3 G/L (20 ºC)

别名和识别编码

Chemical Name	Styrene Oxide
CAS Number	96-09-3
Synonym	1,2-Epoxyethylbenzene, Phenylethylene oxide, Phenyloxirane ######## (1,2-Epoxyethyl)benzene (epoxyethyl)-benzen (±)-2-Phenyloxirane (±)-Styrene oxide 1,2-环氧乙基苯, 环氧苯乙烷 1-Phenyloxirane 2-PHENYLOXIRANE Ep Epoxyethylbenzene Epoxystyrene Ethane, 1,2-epoxy-1-phenyl- Fenyloxiran PHENYLETHYLENE OXIDE Phenyl oxirane Phenyloxirane <undefined optical isomer> STYRENE EPOXIDE Styrene 1',2'-oxide Styrene oxide benzene,(1,2-epoxyethyl) ep-182 {} {Chemical {} {} {Chemicalbook} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {Ch α,β-Epoxystyrene 氧化苯乙烯氧化苯乙
MDL Number	MFCD00005121
Beilstein Registry Number	108582
PubChem Substance ID	87569334
EC Number	202-476-7
Reaxys-RN	108582
Chemical Name Translation	氧化苯乙烯
Wiswesser Line Notation	T3OTJ BR
LabNetwork Molecule ID	LN00193192
InChI	InChI=1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2

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品牌质保精细包装现货库存一流品牌服务

产品应用

医药中间体。用于β-苯乙醇的中间体。

安全信息

GHS Symbol

WGK Germany3

Hazard Codes 6.1 T

Hazard statements

H350 May cause cancer 可能致癌
H319 Causes serious eye irritation 严重刺激眼睛
H302 Harmful if swallowed 吞食有害
H311 Toxic in contact with skin 皮肤接触中毒
H315 Causes skin irritation 会刺激皮肤
H331 Toxic if inhaled 吸入中毒
H312 Harmful in contact with skin 皮肤接触有害
H340 May cause genetic defects 可能导致遗传性缺陷
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H227 Combustible liquid 可燃液体

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSCZ9625000

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312+P330
P302+P350
P302+P352+P312+P361+P364
P304+P340
P304+P340+P312
P305+P351+P338
P305+P351+P338+P337+P313
P308+P313
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P337+P313
P370+P378
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

UN Number 2810 UN2810

Risk Statements

R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
R21 Harmful in contact with skin 与皮肤接触有害
R36 Irritating to eyes 刺激眼睛
R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R45 May cause cancer 可能致癌
R46 May cause inheritable genetic damage 可能引起遗传基因损害

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；

Packing GroupIII

Hazard Class6.1

Storage condition 0-6°C

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 74 gm/kg/62W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   31,41,1963

TYPE OF

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 52 gm/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   MELAAD Medicina del Lavoro.  Industrial Medicine.  (Via S. Barnaba, 8, 20122
   Milan, Italy) V.16-    1925-  Volume(issue)/page/year: 70,358,1979

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 77,471,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 96 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   RARSAM Radiation Research, Supplement.  (New York, NY)  No.1-7, 1959-67.
   Discontinued.  Volume(issue)/page/year: 3,193,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB81-168510

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 890 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 7/21/1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,321,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 77,471,1986

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 70 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 192,239,1987

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 20 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,317,1

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 25 mg/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 8

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 300 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 231,205,1990

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5 ug/well
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 133,161,1984

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - hamster
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   26,305,1979

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/7H
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   SWEHDO Scandinavian Journal of Work, Environment and Health. (Haartmaninkatu
   1, SF-00290 Helsinki, 29, Finland)  V.1-    1975- Volume(issue)/page/year:
   9,94,1983

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/7H
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   SWEHDO Scandinavian Journal of Work, Environment and Health. (Haartmaninkatu
   1, SF-00290 Helsinki, 29, Finland)  V.1-    1975- Volume(issue)/page/year:
   7(Suppl 4),66,1981

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 15 ppm/7H
SEX/DURATION            : female 1-24 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issu

Warnings 危险化学品

其他信息

Acros Organics:氧化苯乙烯 Styrene oxide, 98%(96-09-3)
Sigma Aldrich:96-09-3(sigmaaldrich)
常规方法:200kg镀锌铁桶装。贮存于阴凉、干燥、通风的库房内，远离火种、热源，防潮、防晒，密封贮存。按一般化学品规定贮运。
图谱信息:氧化苯乙烯(96-09-3)核磁图( 13 CNMR) 氧化苯乙烯(96-09-3)红外图谱(IR2) 氧化苯乙烯(96-09-3)红外图谱(IR1) 氧化苯乙烯(96-09-3)Raman光谱氧化苯乙烯(96-09-3)质谱(MS) 氧化苯乙烯(96-09-3)核磁图( 1 HNMR)
下游产品:苯乙醇 --> 苯乙醛
TCI Shanghai:1,2-环氧苯乙烷 Styrene Oxide,>;98.0%(GC)(96-09-3)
Alfa Aesar:(±)-氧化苯乙烯,98+% (+/-)-Styrene oxide, 98+%(96-09-3)
用途一:用于医药、香料中间体
MOL 文件:96-09-3.mol
外观性质:无色至淡黄色液体，有芳香味。
用途二:医药中间体。用于β-苯乙醇的中间体。
溶于水,有芳香气味,,水溶性3g/L(20℃)。
防护措施:参见环氧乙烷（A 125）。
蒸气密度:4.14 (vs air)
海关编码:29109000
氧化苯乙烯价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 E0013 氧化苯乙烯 Styrene Oxide 25ML 80元 2014/06/02 E0013 氧化苯乙烯 Styrene Oxide 500ML 445元 2010/06/21 132800025 氧化苯乙烯 Styrene oxide 98% 2.5 LT 1681元
方法一:1.将42g过氧苯甲酸、30g苯乙烯和400ml氯仿混匀，在0℃保持24h。取样检查，应有略过量的过氧苯甲酸存在。用过量的10%氢氧化钠溶液洗涤反应产物除去苯甲酸。然后水洗除碱，经无水硫酸钠干燥，蒸馏收集188-192℃馏分，得氧化苯乙烯24-26g。2.由苯乙烯、溴化钠、硫酸、液体烧碱经卤醇化反应、皂化反应、精馏而得环氧苯乙烷。
蒸气压:<;1 mm Hg ( 20 °C)
MSDS 信息:氧化苯乙烯(96-09-3).msds
上游原料:氢氧化钠 --> 硫酸 --> 碳酸钠 --> 三氯甲烷 --> 无水醋酸钠 --> 间氯过氧苯甲酸 --> 苯乙烯 --> 氯酸钠 --> 溴化钠 --> 液体烧碱