CAS 109-86-4 MFCD00002867-2-Methoxyethanol 乙二醇单甲醚 TAO{mole}

2-Methoxyethanol 乙二醇单甲醚

CAS 109-86-4 MFCD00002867

化学结构图

SMILES: COCCO

化学属性

Mol. Formula	C3H8O2
Mol. Weight	76.10
Refractive index	1.4010 to 1.4040
Boiling Point	124°C
Density	0.96
Melting Point	-85
Flash Point	41°C(lit.)
Solubility	与水混溶，可混溶于醇、酮、烃类。
TSCA	Yes
Autoignition Point	548 °F
Vapor Density	2.62 (vs air)
Vapor Pressure	6.17 mmHg ( 20 °C)
Stability	对湿度敏感

别名和识别编码

Chemical Name	2-Methoxyethanol
Synonym	2-Methoxy-aethanol 2-Methoxyethanol 2-Metossietanolo Aethylenglykol-monomethylaether Dowanol 7 Dowanol EM Ethylene glycol methyl ether Ethylene glycol monomethyl ether Ethylene glycol monomethyl ether; Methyl cellosolve; Methyl glycol Glycol ether EM Glycol monomethyl ether Glycolmethyl ether Methoxyhydroxyethane Methyl cellosolve Methyl ethoxol Methyl glycol Methyl oxitol Methylglykol Metil cellosolve Metoksyetylowy alkohol Monomethyl ether of ethylene glycol Poly-Solv EM Prist 乙二醇单甲醚甲基乙二醇甲基溶纤剂®
CAS Number	109-86-4
PubChem Substance ID	8019
EC Number	203-713-7
Beilstein Registry Number	1731074
MDL Number	MFCD00002867
Reaxys-RN	1731074
Merck Number	6038
Chemical Name Translation	乙二醇单甲醚
InChIKey	XNWFRZJHXBZDAG-UHFFFAOYSA-N
Wiswesser Line Notation	Q2O1
LabNetwork Molecule ID	LN00163735
InChI	InChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

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产品应用

测定铁；硫酸盐和二硫化碳的试剂，用作各种油脂类；木质素；硝基纤维素；乙酸纤维素；醇溶性染料和合成树脂的溶剂

安全信息

GHS Symbol

WGK Germany2

Hazard Codes 3 T

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
H370 Causes damage to organs 导致器官损伤
H302+H312+H332
H332 Harmful if inhaled 吸入有害
H312 Harmful in contact with skin 皮肤接触有害
H302 Harmful if swallowed 吞食有害

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSKL5775000

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P233 Keep container tightly closed. ?保持容器密闭。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
P241+P242+P243
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P302+P352+P312+P362+P364
P303+P361+P353
P304+P340+P311
P305+P351+P338
P305+P351+P338+P337+P313
P308+P311
P308+P313
P332+P313
P337+P313
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word

UN Number 1188

Risk Statements

R10 Flammable 易燃
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R48/22
R60 May impair fertility 可能降低生殖能力
R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；

Packing GroupIII

Storage condition 密封保存。

Hazard Class3

Warnings 危化品目录(2015)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(issue)/page/year: 1,57,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(issue)/page/year: 1,57,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 3380 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(is

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 3380 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 150 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 320,125,1994

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 175 mg/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 9,1,1986

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/6H
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,43,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 175 mg/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   TJADAB Teratology, The Internation

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/6H
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Fertility - female fertility index (e.g. #

Restrict 危险品

其他信息

具有令人愉快的气味，能与水；乙醇；乙醚；甘油；丙酮；N,N-二甲基甲酰胺混溶。易吸水，有毒，性质稳定。