• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Biotech Solvents, Solvent Bottles, Solvent P
• {SNA} Amber Glass Bottles,
• {Chemicalbook} 农药中间体: 杀菌剂中间体: 三唑类杀菌剂
• {SNA} Alkyl
• {SNA} Anhydrous Solvents, Solvent Bottles, Solvent Packaging Options, Solvent by Application, Solvents, Sure/Seal Bottles
• Amber Glass Bottles, Analytical Reagents, Analytical/Chromatography, CHROMASOLV for HPLC, Chromatography Reagents & Solvents, HPLC & UHPLC Solvents (CHROMASOLV), HPLC Grade Solvents (CHROMASOLV), HPLC/UHPLC Solvents (CHROMASOLV), Solvent Bottles, Solvent Packaging Options, Solvent by Application, Solvents
• {SNA} Amber Glass Bottles, CHROMASOLV for HPLC, Chromatography Reagents & Solvents, HPLC & UHPLC Solvents (

产品应用

• 有机合成。制备丁基纤维素的丁基化剂。溶剂。

相关文献及参考

• Merck:14,1560 Beilstein:1(4)246
• Merck:14,1560
• Short: II/14a
• Short: II/2
• Short: II/24B
• The Grignard reagent has been recommended as superior to EtMgBr for the preparation of ethynyl magnesium halides from acetylene. For details, see: Org. Synth. Coll., 8, 606 (1993); for generation and use of the Grignard in the Mn-Cu catalyzed 1,4-addition to an enone, see: Org. Synth. Coll., 9, 328 (1998).

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VRDEA5 Vrachebnoe Delo.  Medical Practice.  (V/O Mezhdunarodnaya Kniga,
   113095 Moscow, USSR) No.1-    1918-  Volume(issue)/page/year: (7),105,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 10,61,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 44(3),11,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,745,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        :

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 500 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-312,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 13927 mg/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 44(3),11,1979

其他信息

• Sigma Aldrich:109-69-3(sigmaaldrich)
• TCI Shanghai:1-氯正丁烷 1-Chlorobutane,>;98.0%(GC)(109-69-3)
• 下游产品:正丁基锂 --> 3-(4-甲氧基-6-甲基-1,3,5-三嗪-2-基)-1-(2-甲氧基甲酰基苯基)磺酰脲 --> 正丁胺 --> 6-溴吡啶-2-甲醛 --> 叔丁基苯 --> 氧化二乙酰丙酮合钒 --> 腈菌唑 --> 2-正丁基-2-苯基-3-(1H-咪唑-1-基)丙腈 --> Α-丁基-Α-苯基-1H-咪唑-1-丙腈 --> 二丁基氧化锡 --> 正丁基丙二酸二乙酯 --> 三丁基氧化锡 --> 1,4-二氯丁烷 --> 1-正丁基-1-甲基吡咯烷二(三氟甲基磺酰)酰亚胺,98% -
• 图谱信息:1-氯丁烷(109-69-3)核磁图( 13 CNMR) 1-氯丁烷(109-69-3)红外图谱(IR2) 1-氯丁烷(109-69-3)质谱(MS) 1-氯丁烷(109-69-3)核磁图( 1 HNMR) 1-氯丁烷(109-69-3)红外图谱(IR1)
• 上游原料:盐酸 --> 正丁醇 --> 氯化锌
• 灭火剂:干粉、二氧化碳、泡沫, 水雾
• 方法二:由正丁醇与氯化氢反应而得：正丁醇和浓盐酸在氯化锌存在下加热回流反应，将反应物用水洗涤、干燥，分馏，收集75-78.5℃馏分即为成品。原料消耗定额：正丁醇（95%）1600kg/t、盐酸（30%）2780kg/t。
• {Chemicalb
• 蒸气压:80.1 mm Hg (
• 用途五:在医药工业中，用作合成动物驱虫剂和保泰松药物的原料，在有机合成中，用作合成月桂酸二丁基铝、丁基纤维素等的原料。另
• 毒性分级:中毒
• 用途二:用作溶剂，也用于有机合成
• 可燃性危险特性:遇明火、高温、氧化剂易燃; 遇热分解有毒光气; 燃烧产生有毒氯化物烟雾
• 类别:易燃液体
• 用途六:109-69-3（1-氯丁烷）用于制备烯烃聚合催化剂——丁基锂，格氏反应：制备丁基锡类产品，1-氯丁烷（109-69-3）在医药制备保泰松，农药方面：制备杀虫剂腈菌唑等聚醚生产作溶剂
• Alfa Aesar:1-氯丁烷,HPLCGrade,99.5+% 1-Chlorobutane, HPLC Grade, 99.5+%(109-69-3)
• 用途七:有机合成。制备丁基纤维素的丁基化剂。溶剂。
• 方法一:其制备方法是将丁醇与氯化氢在催化剂ZnCl 2 存在下进行反应，反应结束后洗涤、干燥、分馏得产品。反应方程式：CH 3 CH 2 CH 2 CH 2 OH+HCl[ZnCl 2 ]→CH 3 CH 2 CH 2 CH 2 Cl+H 2 O
• 用途三:用作溶剂及有机合成中丁基化试剂，还可用于制造丁基纤维素、驱虫剂及赛璐珞、保泰松等
• 职业标准:TWA 1.5 毫克/立方米; STEL 1.5 毫克/ 立方米
• Acros Organics:1-氯丁烷 1-Chlorobutane, 99+%(109-69-3)
• 用途一:用于油脂、橡胶、天然树脂溶剂、医药中间体、助催化剂等
• 能与乙醇和乙醚混溶，几乎不溶于水，溶解度: 0.5 g/l水 (20°C)。易燃
• 急性毒性:口服- 大鼠 LD50: 2670 毫克/ 公斤; 未报-小鼠 LD50: 5600 毫克/公斤
• 1-氯丁烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80024890 氯代正丁烷 500ml 470元 2011/08/23 80024826 氯代正丁烷 100ml 44.5元 2011/08/23 FB429401 氯代正丁烷 4L 1780元
• 储运特性:库房通风低温干燥; 与氧化剂、酸类分开存放
• 爆炸物危险特性:与空气混合可爆; 与二价金属反应生成爆炸产物.