3-(Chloromethyl)pyridine hydrochloride 3-(氯甲基)吡啶盐酸盐
CAS 6959-48-4 MFCD00012818
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资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
相关文献及参考
- The free base can be lithiated at the methylene group by treatment with LDA in THF at -78o. The resulting (3-pyridinylchloromethyl)lithium can be trapped by reaction with various electrophiles at low temperatures: J. Org. Chem., 61, 4148 (1996).
安全信息
GHS Symbol
- S24 Avoid contact with skin 避免皮肤接触;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- R22 Harmful if swallowed 吞咽有害
- R34 Causes burns 会导致灼伤
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P234 Keep only in original container. 只保留在原来的容器中。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P330+P331
- P301+P330+P331+P310
- P303+P361+P353+P310+P363
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
- P405 Store locked up. 上锁保管。
- P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H290 May be corrosive to metals 可能腐蚀金属。
- H302 Harmful if swallowed 吞食有害
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 37 gm/kg/83W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application REFERENCE : NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-95,1978
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 49 gm/kg/81W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application REFERENCE : NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-95,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 316 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year: NCI-E-C-72-3252,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 316 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) Volume(issue)/page/year: NCI-E-C-72-3252,1973
TYPE OF TEST : Morphological transformation TEST SYSTEM : Rodent - rat Embryo DOSE/DURATION : 640 ng/plate REFERENCE : JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 1,190,1981
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 20 ppm REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 23,208,1994
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 33300 ng/plate REFERENCE : ENMUDM Environment
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 5 mg/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,143,1987
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 76200 nmol/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19,98,1992
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 13100 ug/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988
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其他信息
- MSDS 信息:3-Picolyl chloride hydrochloride(6959-48-4).msds
- 类别:有毒物质
- 灭火剂:水, 二氧化碳, 干粉, 砂土
- 毒性分级:高毒
- F:3-10
- 下游产品:3-(2-氨基乙基)吡啶 --> N-甲基-N-(3-甲基吡啶)胺 --> 1-[(3-吡啶)甲基]哌嗪 --> 3-吡啶乙酸
- TCI Shanghai:3-(氯甲基)吡啶盐酸盐 3-(Chloromethyl)pyridine Hydrochloride,>;98.0%(T)(6959-48-4)
- Alfa Aesar:3-氯甲基吡啶盐酸,97% 3-(Chloromethyl)pyridine hydrochloride, 97%(6959-48-4)
- 可燃性危险特性:可燃, 燃烧时分解有毒氯化物, 氮氧化物气体
- Acros Organics:3-氯甲基吡啶盐酸盐 3-Picolyl chloride hydrochloride, 99%(6959-48-4)
- 储运特性:库房低温, 通风, 干燥 ; 防火; 与氧化剂, 食品原料分开存放
- 急性毒性:口服- 大鼠 LD50: 316 毫克/ 公斤; 口服- 小鼠 LD50: 316 毫克/ 公斤
- 检测方法:HPLC
- Hazard Note:Corrosive
- 敏感性:Hygroscopic
- 海关编码:29333999
- 3-氯甲基吡啶盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0825 3-(氯甲基)吡啶盐酸盐 3-(Chloromethyl)pyridine Hydrochloride 100G 1820元 2014/06/02 C0825 3-(氯甲基)吡啶盐酸盐 3-(Chloromethyl)pyridine Hydrochloride 25G 636元 2010/06/21 131190250 3-氯甲基吡啶盐酸盐 3-Picolyl chloride hydrochloride 99% 25 GR 742元
- MOL 文件:6959-48-4.mol
- 用途一:用作医药中间体
- 图谱信息:3-氯甲基吡啶盐酸盐(6959-48-4)核磁图( 13 CNMR) 3-氯甲基吡啶盐酸盐(6959-48-4)质谱(MS) 3-氯甲基吡啶盐酸盐(6959-48-4)核磁图( 1 HNMR)