CAS 89-63-4 MFCD00007836-4-Chloro-2-nitroaniline 4-氯-2-硝基苯胺 TAO{mole}

4-Chloro-2-nitroaniline 4-氯-2-硝基苯胺

CAS 89-63-4 MFCD00007836

化学结构图

SMILES: Nc1ccc(Cl)cc1[N+](=O)[O-]

化学属性

Mol. Formula	C6H5ClN2O2
Mol. Weight	173
Melting Point	117-119
Density	1.37
Flash Point	191°(375°F)
TSCA	Yes
Autoignition Point	964 °F
Solubility	不溶

别名和识别编码

Chemical Name	4-Chloro-2-nitroaniline
CAS Number	89-63-4
Synonym	1-Amino-2-nitro-4-chlorbenzol 1-Amino-4-chloro-2-ni 1-Amino-4-chloro-2-nitrobenzene 2-NITRO-4-CHLOROANI 2-Nitro- 2-硝基-4-氯苯胺 4-CHLORO-2-NITROANILINE 4-Chloro-2-nitroaniline 4-Chloro-2-nitrobenz 4-chloro-2-nitro-anilin p-Chlor-o-nitroanilin p-Chloro-o-nitroaniline Aniline, 4-chloro-2-nitro- C.I. Azoic Diazo Com Daito Red FAST RED 3GL BASE Fast Red 2NC Salt Fast Red 3GL Base Fast Red Base 3GL Special Fast Red Salt 3GL Fast Red Salt 3JL Kayaku Fast Red 3GL Base Naphthanil Red 3G Base Naphtoelan Fast Red 3GL Base PCON RED 3G BASE {} {Chemicalbook {} {} {ALD} {} {} {} {} {Chemi {} {} {} {} {
PubChem Substance ID	6979
EC Number	201-925-4
Beilstein Registry Number	512436
MDL Number	MFCD00007836
Reaxys-RN	512436
Chemical Name Translation	4-氯-2-硝基苯胺
Wiswesser Line Notation	ZR DG BNW
LabNetwork Molecule ID	LN00008073
InChI	InChI=1S/C6H5ClN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2

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品牌质保精细包装现货库存一流品牌服务

产品应用

冰染染料色基，用于制取大红色淀、嫩黄10G色淀等有机颜料和染料。用作棉、粘胶织物的印染显色剂，也可用于丝绸、涤纶织物的印染。

安全信息

GHS Symbol

WGK Germany2

Hazard statements

H300+H310+H330
H301+H311+H331
H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
H330 Fatal if inhaled 吸入致命
H310 Fatal in contact with skin 皮肤接触致命
H300 Fatal if swallowed 吞食致命

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes 6.1 T+,N T+,N,T

RTECSBX1575000

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P301+P310
P302+P350
P304+P340+P311
P308+P313
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

UN Number 2237

Safety Statements

S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
R33 Danger of cumulative effects 有累积作用的危险
R51/53

Packing GroupIII

Hazard Class6.1

Warnings 危化品目录(2015)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 63 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 302 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 20 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

Restrict 危险品

其他信息

下游产品:精喹禾灵 --> 耐晒黄10G --> 紫外线吸收剂 UV-327 --> N-乙酰基-N-(4-氯-2-硝基苯基)乙酰胺 --> 分散黄 C-4G
Acros Organics:4-氯-2-硝基苯胺 4-Chloro-2-nitroaniline, 99%(89-63-4)
可燃性危险特性:遇热分解放出有毒苯胺、氮氧化物和氯化物气体
类别:有毒物品
不溶于水，溶于乙醇、乙醚和乙酸，微溶于粗汽油。
用途二:对氯邻硝基苯胺是除草剂喹禾灵的中间体，也是染料中间体。
MOL 文件:89-63-4.mol
方法二:以 1，4-二氯-2-硝基苯为原料，经氨化制得。氨化反应可以在高压釜内间歇进行，即用 27%氨水，温度 170-175℃，压力 32-35Pa，约 2.5h 内完成，后经精制得成品。氨化反应也可在管式反应器内连续进行，即用 27%氨水，温度 205-208℃，压力 200Pa。。将 1，4-二氯-2-硝基苯 28L/h 和 27%氨水 140L/h (两者的物质的量比为 1:10) 以及 80℃水 50L/h 分别经计量槽用泵送往混合喷嘴，混合后经预热器加热至 180℃，然后加入蛇管区，管内温度为 205-208℃。反应在两个塔内完成，塔的内径为 90mm，长 4m，塔内压力 200Pa，压力的调节依靠膨胀器前面的减压阀进行。4-氯-2-硝基苯胺、水、氯化铵和过量的氨经减压阀放出，沿切线方向进入膨胀器后减为常压，膨胀器内温度约 85℃，通过膨胀器顶部喷洒热的冷凝水控制。大部分过量的氨经冷却器去氨吸收塔回收。膨胀器内黏稠物被加热至 80-90℃，以蒸发出更多的氨。黏稠物内含有微细分散的 4-氯-2-硝基苯胺、氯化铵涪液和 3%游离氨。黏稠物通过螺旋出料器取出后，进行抽滤，得到产品 4-氯-2-硝基苯胺，熔点 114-114.5℃。若其他条
方法三:以2,5-二氯硝基苯与液氨为原料，先经加压氨解、结晶，然后过滤、干燥而得。原料消耗定额：2,5-二氯硝基苯（工业品）1167kg/t、液氨（工业品）230kg/t、氨水（工业品）2420kg/t。
Sigma Aldrich:89-63-4(sigmaaldrich)
急性毒性:口服-大鼠 LD50: 400 毫克/公斤; 口服-小鼠 LD50: 800 毫克/公斤
色
4-氯-2-硝基苯胺价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0215 4-氯-2-硝基苯胺 4-Chloro-2-nitroaniline 500G 682元 2014/06/02 C0215 4-氯-2-硝基苯胺 4-Chloro-2-nitroaniline 25G 137元 2010/06/21 146521000 4-氯-2-硝基苯胺 4-Chloro-2-nitroaniline 99% 100 GR 156元
上游原料:2,5-二氯硝基苯
海关编码:29214210
储运特性:库房通风低温干燥; 与食品原料分开储运
用途一:用于生产颜料耐晒黄10G、分散黄211、紫外线吸收剂UV-326
TCI Shanghai:4-氯-2-硝基苯胺 4-Chloro-2-nitroaniline,>;98.0%(GC)(89-63-4)
灭火剂:二氧化碳、砂土、泡沫、雾状水
Hazard Note:Very Toxic
用途三:红色基 3GL 主要用于棉的染色和棉布的印花，也用于黏胶纤维、蚕丝、涤纶的染色。与色酚 AS-OL 偶合染枣红色。偶合能力强，偶合速度快。也用于制造有机颜料的中间体。
图谱信息:4-氯-2-硝基苯胺(89-63-4)质谱(MS) 4-氯-2-硝基苯胺(89-63-4)核磁图( 13 CNMR) 4-氯-2-硝基苯胺(89-63-4)核磁图( 1 HNMR) 4-氯-2-硝基苯胺(89-63-4)红外图谱(IR1) 4-氯-2-硝基苯胺(89-63-4)红外图谱(IR2)