2-Aminobenzoic acid 2-氨基苯甲酸(一类易制毒,不能销售)
CAS 118-92-3 MFCD00007712
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资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
一流品牌服务
分类
- Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents, Carbohydrate Labels, Carbohydrate Labels for Chromatography, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Fluorophores, Glycan Labeling, Glycan Labeling and Analysis, Glycobiology, Mass Spectrometry (MS), Matricies for Mass Spectroscopy Analysis of Glycans, Matrix Substances for MALDI-MS, Post-Translational Modification, Proteomics, Spectroscopy
- {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; carboxylic acid; 1fragment
- {SNA} Glycan Labeling and Analysis, Glycobiology, Matricies for Mass Spectroscopy Analysis of Glycans, Post-Translational Modification, Proteomics
相关文献及参考
- 1. Bigge J.C., et al., Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. Anal. Biochem. 230 , 229-238, (1995) 摘要
- 2. Anumula, K.R., Quantitative determination of monosaccharides in glycoproteins by high-performance liquid chromatography with highly sensitive fluorescence detection. Anal. Biochem. 220 , 275-283, (1994) 摘要
- 3. Anumula, K.R. and Dhume, S.T., High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid. Glycobiology 8 , 685-60, (1998)
- 4. Kae Sato, L., et al., Optimization of derivatization with 2-aminobenzoic acid for determination of monosaccharide composition by capillary electrophoresis. Anal. Biochem. 262 , 195-197, (1998) 摘要
- Huang, Z., et al., The use of the 2-aminobenzoic acid tag for oligosaccharide gel electrophoresis. Carbohydr. Chem. 328 , 77-83, (2000) 摘要
- He, L., et al., Separation of saccharides derivatized with 2-aminobenzoic acid by capillary electrophoresis and their structural consideration by nuclear magnetic resonance. Anal. Biochem. 314 , 128-134, (2003) 摘要
- Neville, D.C., et al., Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling. Anal. Biochem. 331 , 275-282, (2004) 摘要
- Merck 14 ,422
- Beil. 14 ,IV,1004
- Aldrich MSDS 1 , 131:A / Corp MSDS 1 (1), 282:B / FT-IR 1 (2), 189:A / FT-IR 2 (2), 2651:B / FT-NMR 1 (2), 1066:B / IR-Spectra (2), 838:G / IR-Spectra (3), 958:B / NMR-Reference 2 (2), 186:B / RegBook 1 (2), 1783:N / Sax 6 , 291 / Sigma FT-IR 1 (2), 291:B / Structure Index 1 ,
安全信息
GHS Symbol
- H318 Causes serious eye damage 严重伤害眼睛
- H319 Causes serious eye irritation 严重刺激眼睛
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P337+P313
- S39 Wear eye/face protection 戴眼睛/面孔保护装置;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- R36 Irritating to eyes 刺激眼睛
- R37 Irritating to respiratory system 刺激呼吸道
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1345 mg/kg/21D-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Liver - tumors REFERENCE : JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 96,163,1980
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2040 mg/kg female 13-17 day(s) after conception TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Liver - tumors REFERENCE : JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 96,163,1980
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 16 gm/kg/25W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors REFERENCE : APMIAL Acta Pathologica et Microbiologica Scandinavica. (Copenhagen, Denmark) V.1-77, 1924-69. For publisher information, see ACPADQ. Volume(issue)/page/year: 26,447,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5410 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - ataxia REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(3),52,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 19,483,1946
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,1392,1990
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - wild bird species DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 1266 mg/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - mouse Lymphocyte DOSE/DURATION : 250 mg/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 1667 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 196,61,1988
TYPE OF TEST : Sister chromatid exchange ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 600 mg/kg REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 14,207,1989
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 34800 mg/kg SEX/DURATION : male 8 day(s) pre-mating female 21 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,7,1966
其他信息
- Acros Organics:邻氨基苯甲酸(0402限出口) Anthranilicac
- 常规方法:采用内衬聚乙烯塑料袋、外套
- 用途二:用作络合试剂及实验试剂
- 毒性分级:中毒
- 邻氨基苯甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30007326 邻氨基苯甲酸(易制毒-1) 100g 115元 2010/06/21 104910050 邻氨基苯甲酸 Anthranilic acid 98+% 5 GR 164元 2010/06/21 104915000 邻氨基苯甲酸 Anthranilic acid 98+% 500 GR 334元
- 下游产品:2-碘苯甲酸 --> 邻氟苯甲酸 --> 4-氯喹唑啉 --> N-苯基邻氨基苯甲酸 --> 2-氨基-5-碘苯甲酸 --> 2-氯噻吨酮 --> 氯氮平 --> 甲基红 --> 1,3-苯并二硫代吡咯四氟化硼盐 --> 6-碘喹唑啉-4-酮 --> 2-氯-9-[3-(二甲基氨基)丙基]噻吨-9-醇 --> 2-肼基苯甲酸盐酸盐 --> 4-羟基喹唑啉 --> 直接耐晒棕 8RLL --> 3-吲唑啉酮 --> 还原红棕 RRK --> 2-二甲基氨基苯甲酸 --> 荧光增白剂PF --> 3-氨基邻苯二甲酸酐 --> 氯苯扎利 --> 2-氨基-5-溴苯甲酸 --> 2-氨基苯甲酸乙酯 --> 分散黄 5G --> 活性蓝X-R --> 1-苄基-3-羟基-1H-吲唑 --> 直接铜盐灰 GRL --> 直接耐晒枣红 BL --> 还原红 41 --> 2-氨基-苯甲酸-2-苯乙酯 --> 2-乙酰氨基苯甲酸 --> 3,5-二溴苯甲酸 --> 2,5-二溴苯甲酸 --> 曲尼司特 --> 吩嗪-1-羧酸 --> 2,2'-二硫代二苯甲酸 --> N-(2-羧基)苯基甘氨酸 --> 靛红酸酐
- {Chemi
- 方法一:由苯酐与氨进行酰胺化反应,生成邻甲酰氨基苯甲酸钠,经次氯酸钠降解反应,生成邻氨基苯甲酸钠,最后中和而得。原料消耗定额苯酐(熔点128-131℃)1340kg/t、次氯酸钠(有效氯≥10%) 6484kg/t、氨水(≥16%)2350kg/t、液碱(30%)2924kg/t。
- MOL 文件:118-92-3.mol
- 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
- Alfa Aesar:邻氨基苯甲酸,98+% Anthranilic acid, 98+%(118-92-3)
- 海关编码:29224300
- 上游原料:氢氧化钠 --> 盐酸 --> 硫酸 --> 氢氧化铵 --> 氯 --> 次氯酸钠 --> 苯酐 --> Α-球蛋白 --> 活性炭 --> 苯
- MSDS
- 类别:易燃液体
- 蒸气密度:4.7 (vs air)
- 急性毒性:口服-小鼠 LD50: 1400 毫克/公斤; 腹腔-小鼠 LD50: 2500 毫克/公斤
- {Che
- 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物烟雾
- 储运特性:库房通风低温干燥
- 上游原料:氢氧化钠 --> 盐酸 --> 硫酸 --> 氢氧化铵
- 图谱信息:邻氨基苯甲酸(118-92-3)红外图谱(IR2) 邻氨基苯甲酸(118-92-3)红外图谱(IR3) 邻氨基苯甲酸(118-92-3)核磁图( 1 HNMR) 邻氨基苯甲酸(118-92-3)红外图谱(IR1) 邻氨基苯甲酸(118-92-3)质谱(MS)
- 用途一:用作染料、医药、香料的中间体
- 用途三:染料、医药、农药、香料的中间体。在染料方面,用于制造偶氮染料、蒽醌染料、靛族染料。例如分散黄GC、分散黄5G、分散橙GG、活性棕K-B3Y、中性蓝BNL。在医药方面,用于制造抗心律失常药常咯啉、维生素L,非甾体类抗炎
- 防护措施:具有中等毒性.刺激皮肤及粘膜.接触皮肤后迅速用水冲洗。生产车间应通风良好,设备应密闭。操作人员应穿戴防护用具。