CAS 695-34-1 MFCD00006321-2-Amino-4-picoline 2-氨基-4-甲基吡啶 TAO{mole}

2-Amino-4-picoline 2-氨基-4-甲基吡啶

CAS 695-34-1 MFCD00006321

化学结构图

SMILES: Cc1ccnc(N)c1

化学属性

Mol. Formula	C6H8N2
Mol. Weight	108
Flash Point	118°(244°F)
TSCA	Yes
Melting Point	98.0 to 101.0 deg-C
Boiling Point	230 °C(lit.)
Density	1.068
Solubility	Soluble in water (41 mg/ml at 20 °C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.
Stability	对湿度敏感

别名和识别编码

Chemical Name	2-Amino-4-picoline
CAS Number	695-34-1
Alfabeta Name	AMINOMETHYLPYRIDINE 24---
MDL Number	MFCD00006321
Synonym	Ascensil 4-Picolylamine 2-氨基-4-皮考林;4-甲基-2-吡啶胺;4-甲基-2-氨基吡啶 Aminopicoline 2-Pyridinamine, 4-methyl- alpha-Amino-gamma-picoline 2-Amino-4-methylpyridine NSC 176165 4M2AP Pyridine, 2-amino-4-methyl- 4-甲基-2-氨基吡啶 NSC 1490 2-氨基-4-甲基吡啶 NSC 6972 2-Amino-γ-picoline 4-Methyl-2-pyridylamine 4-Methyl-2-pyridinamine 4-methyl-pyridin-2-ylamine 2-Amino-4-methylpyridine; 4-Methylpyridin-2-amine Methyl-4 amino-2-pyridine 2-Amino-4-picoline 2-氨基-4-皮考林 W 45 Raschig 4-methylpyridin-2-amine 2-amino-4-methyl-pyridine 4-methyl-(2)pyridylamine RA 1226 4-Picoline, 2-amino- VMI 20-4 4-Methyl-2-aminopyridine W 45
EC Number	211-780-9
Merck Number	466
Beilstein Registry Number	22(2)342
PubChem Substance ID	87562037
Chemical Name Translation	2-氨基-4-甲基吡啶
Reaxys-RN	107066
Wiswesser Line Notation	T6NJ BZ D1
LabNetwork Molecule ID	LN00008181
InChI	InChI=1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

A potent inhibitor of NOS2 (iNOS)

安全信息

Warnings IRRITANT

RTECSTJ5150000

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；

UN Number 2811 UN2811

Risk Statements

R33 Danger of cumulative effects 有累积作用的危险
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R25 Toxic if swallowed 吞咽有毒
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
R21 Harmful in contact with skin 与皮肤接触有害
R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性

Storage condition 充氩保存 Hygroscopic

Signal word Danger Warning

GHS Symbol

WGK Germany3

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P310
P301+P310+P330
P302+P350
P302+P352+P312+P361+P364
P305+P351+P338
P305+P351+P338+P337+P313
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P332+P313
P337+P313
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H301 Toxic if swallowed 吞食有毒
H301+H311
H301+H311+H331
H311 Toxic in contact with skin 皮肤接触中毒
H331 Toxic if inhaled 吸入中毒
H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Packing GroupIII

Hazard Codes T

Hazard Class6.1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   53,227S,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,841,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 227,234,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 26,345,1968

TYPE OF TES

其他信息

2-Amino-4-methylpyridine is a potent inhibitor of NOS2 (iNOS) in vitro.
水中溶解度:41 g/L (20°C)，溶于小分子醇，微溶于石油醚。