CAS 1310-58-3 MFCD00002192-氢氧化钾粉末氢氧化钾粉末 TAO{mole}

氢氧化钾粉末氢氧化钾粉末

CAS 1310-58-3 MFCD00002192

化学结构图

SMILES: [K+].[OH-]

化学属性

Mol. Formula	HKO
Mol. Weight	56
Boiling Point	100
Melting Point	133-134
Density	1.05
TSCA	Yes
Vapor Density	4.4 (vs air)
Vapor Pressure	10 mmHg ( 167.7 °C)
Refractive index	n20/D 1.387
Solubility	Pyrogallol is a benzene triol compound described as a metal-complexing agent. Incubation of plasmid DNA with an NO-releasing NONOate and Pyrogallol demonstrated a synergistic induction of single-strand DNA breakage.
Stability	对光线、空气敏感

别名和识别编码

Chemical Name	氢氧化钾粉末
CAS Number	1310-58-3
Alfabeta Name	BENZENETRIOL 123--,,
MDL Number	MFCD00002192
Synonym	1,2,3-Benzenetriol 1,2,3-Benzenetriol; 1,2,3-Trihydroxybenzene; C.I. 76515 1,2,3-Trihydroxybenzene 1,2,3-苯三酚 Benzene, 1,2,3-trihydroxy- C.I. 76515 C.I. Oxidation Base 32 Fourrine PG Pyrogallussäure benzene-1,2,3-triol pyrogallol 焦性没食子酸溶液邻苯三酚
PubChem Substance ID	14797
EC Number	215-181-3
Beilstein Registry Number	907431
Reaxys-RN	907431
Merck Number	8000
Chemical Name Translation	氢氧化钾粉末
Wiswesser Line Notation	QR BQ CQ
InChI	InChI=1S/K.H2O/h;1H2/q+1;/p-1

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分类

{SNA} Drying Agents, 分析/色谱, 分析试剂, 特定应用试剂
{SNA} Enzyme
{SNA} Additional Standards, Alcohols and Phenols, Alphabetical Index of Phytochemical Standards, Analytical Standards, Betula, Chromatography, Colors, Food and Cosmetic Component Standards, Life Sciences Standards, N - R, Natural Compounds, Phytochemical Standards, Phytochemical Standards by Plant Genus, Standards for Personal Care and Cosmetic Products, neats, prohibited substances (EU-REGULATION No 1223/2009), 分析/色谱
{SNA} Building Blocks, Chemical Synthesis, Hypericum perforatum (St John's wort), Organic Building Blocks, Oxyg

产品应用

A metal-complexing benzene triol compound.

安全信息

Warnings IRRITANT

GHS Symbol

WGK Germany1

Hazard Codes 8 Xn

Hazard statements

H332 Harmful if inhaled 吸入有害
H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H302+H312+H332
H331 Toxic if inhaled 吸入中毒

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges dust mask type N95 (US), Eyeshields, Faceshields, Gloves Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSUX2800000

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P301+P312+P330
P302+P350
P303+P361+P353
P305+P351+P338
P308+P313
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P332+P313
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P501a

Signal word Danger Warning

Safety Statements

S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S51 Use only in well-ventilated areas 仅在通风良好的场所使用；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R22 Harmful if swallowed 吞咽有害
R35 Causes severe burns 会导致严重灼伤
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性

UN Number 1814 1814/2811

Storage condition Light Sensitive 充氩保存 Air & Light Sensitive 密封避光保存。

Packing GroupII

Hazard Class6.1

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3950 mg/kg/58W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 20,117,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - other changes
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,507,1969

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 1,254,1955

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TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 1,254,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percen

TYPE OF TEST            : LD50 - Lethal do

TYPE OF TEST            :

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
   AJVRAH American Journal of Veterinary Research.  (American Veterinary
   Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.1-    1940-
   Volume(issue)/page/year: 23,1264,1962

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 504 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 90,91,1981

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 50 mg/L
REFERENCE :
   ESKGA2 Eisei Kagaku.  Hygienic Chemistry.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1-    1953-
   Volume(issue)/page/year: 32,171,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 25 umol/L
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 82,81,1989

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 252 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 90,91,1981

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 125 mmol/L
REFERENCE :
   MUREAV Mutation Resear

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 300 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 135,109,1984

TYPE OF TEST

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 2(4),325,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   57,466,1955

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其他信息

Pyrogallol is a benzene triol compound described as a metal-complexing agent. Incubation of plasmid DNA with an NO-releasing NONOate and Pyrogallol demonstrated a synergistic induction of single-strand DNA breakage.
无气味。在露光的空气中变成浅灰色。慢慢加热开始升华。溶解度：400 g/L水 (25°C)，1 g/1.3 mL乙醇，1 g/1.6 mL乙醚，微溶于苯、氯仿和二硫化碳。其水溶液在空气中变深，在碱性溶液中则更快。低毒，半数致死量(大鼠，经口)789mg/kg。有刺激性。