CAS 69-78-3 MFCD00007140-Benzoic acid, 3,3'-dithiobis[6-nitro- 5,5'-二硫双(2-硝基苯甲酸) TAO{mole}

Benzoic acid, 3,3'-dithiobis[6-nitro- 5,5'-二硫双(2-硝基苯甲酸)

CAS 69-78-3 MFCD00007140

化学结构图

SMILES: O=C(O)c1cc(SSc2ccc([N+](=O)[O-])c(C(=O)O)c2)ccc1[N+](=O)[O-]

化学属性

Mol. Formula	C14H8N2O8S2
Mol. Weight	396.35
Density	1.6412
Melting Point	243-245°C
TSCA	Yes
Stability	热敏感
Solubility	Soluble in 100% ethanol, dioxane, and Phosphate buffer.
Boiling Point	671.9°C at 760 mmHg
Flash Point	360.1°C

别名和识别编码

Chemical Name	Benzoic acid, 3,3'-dithiobis[6-nitro-
Synonym	DTNB {LY} DTNB {} {LY} DTNB {} {} {LY} DTNB {} {} {} {LY} DTNB {} {} {} {} {LY} DTNB {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DTNB {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number	MFCD00007140
CAS Number	69-78-3
EC Number	200-714-4
Beilstein Registry Number	1896821
PubChem Substance ID	87567535
Alfabeta Name	CARBOXYNITROPHENYLDITHIONITROBENZOICACID 5342[]()------
Chemical Name Translation	5,5'-二硫双(2-硝基苯甲酸)
Reaxys-RN	1896821
Merck Number	3551
LabNetwork Molecule ID	LN00182824
InChI	InChI=1S/C14H8N2O8S2/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20/h1-6H,(H,17,18)(H,19,20)
Canonical SMILES	O=C(O)C1=C([N+]([O-])=O)C=CC(SSC2=CC(C(O)=O)=C([N+]([O-])=O)C=C2)=C1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

巯基测定，是测定蛋白质、多肽和组织中巯基的灵敏试剂。也用于有机磷农药中毒的监测（胆碱酯酶测定）。

安全信息

Signal word Warning

GHS Symbol

WGK Germany3

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S37 Wear suitable gloves 戴适当手套；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用

RTECSDG9650000

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

Warnings IRRITANT

Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2080 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,284,1971

其他信息

Highlights:
Highlights: ?Sulfhydryl assay – reacts quantitatively with free (reduced) sulfhydryl groups (–SH) to yield detectable TNB product ?Colorimetric detection – colored product enables spectrophotometric measurement in cuvettes or microplates (λmax = 412nm; ε = 14,150/M?cm) ?Proven method – well-characterized chemistry provides quantitation of peptide or protein sulfhydryl groups using extinction coefficient calculation or by comparison to a cysteine standard
Alfa Aesar:5,5'-二硫双(2-硝基苯甲酸),99% 5,5'-Dithiobis(2-nitrobenzoic acid), 99%(69-78-3)
{Chemi
TCI Shanghai:5,5'-二硫代双(2-硝基苯甲酸)[用于巯基基团的测定] 5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups],>;98.0%(T)(69-78-3)
用途一:广泛用于生化研究，是生化反应色原，诊断试剂研究生产，测定蛋白质、多肽和组织中巯基的灵敏测定试剂。有机磷农药中毒的监测（胆碱酯酶测定）。
海关编码:29309070
Ellman's Reagent (5,5'-dithio-bis-[2-nitrobenzoic acid]) is used to estimate sulfhydryl groups in a sample by comparing to a standard curve of a sulfhydryl-containing compound such as cysteine. Alternatively, sulfhydryl groups can be assayed using the extinction coefficient of TNB (14,150M-1cm-1 at 412nm). Ellman's Reagent has been used for applications other than sulfhydryl estimation, such as for determining alkylthiols by HPLC using a pre-column derivatization procedure and to study thiols in the active site of several enzymes.
MOL 文件:69-78-3.mol
Ellman's Reagent (DTNB) reacts with sulfhydryl groups to yield a colored product, providing a reliable method to measure reduced cysteines and other free sulfhydryls in solution.
5,5'-二硫双(2-硝基苯甲酸)价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 30078984 5，5’-二硫代双（2-硝基苯甲酸） 5g 650元 2011/08/23 L0986802 5.5’-二硫代双（2-硝基苯甲酸）99％ 5g 607元 2011/04/16 D0944 5,5'-二硫代双(2-硝基苯甲酸)[用于巯基基团的测定] 5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups] 5G 776元
MSDS 信息:3-Carboxy-4-nitrophenyl disulfide(69-78-3).msds
F:10