CAS 50-32-8 MFCD00003602-Benzo[a]pyrene 苯并(a)芘 TAO{mole}

Benzo[a]pyrene 苯并(a)芘

CAS 50-32-8 MFCD00003602

化学结构图

SMILES: c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34

化学属性

Mol. Formula	C20H12
Mol. Weight	252.31
Melting Point	177-180 °C
Solubility	不溶于水，微溶于乙醇、甲醇，溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。
TSCA	Yes
Boiling Point	495 °C at 760 mmHg
Flash Point	495°C
Density	1.286
Stability	对光线敏感

别名和识别编码

Chemical Name	Benzo[a]pyrene
CAS Number	50-32-8
Synonym	Benzo[a]pyrene {LY} Benzo[a]pyrene {} {LY} Benzo[a]pyrene {} {} {LY} Benzo[a]pyrene {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[a]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}
MDL Number	MFCD00003602
Reaxys-RN	1911333
Merck Number	1103
Beilstein Registry Number	5(3)2517
PubChem Substance ID	2336
EC Number	200-028-5
Chemical Name Translation	苯并(a)芘
Wiswesser Line Notation	L D6 B6666 2AB TJ
LabNetwork Molecule ID	LN00189340
InChI	InChI=1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H
Canonical SMILES	C12=C(C=C3)C=C(C=CC=C4)C4=C1C=CC5=CC=CC3=C25

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产品应用

本品在工业上无生产和使用价值，一般只作为生产过程中形成的副产物随废气排放。

安全信息

RTECSDJ3675000

UN Number UN3077

Signal word

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P302+P352
P302+P352+P333+P313+P362+P364
P308+P313
P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P333+P313
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
H315 Causes skin irritation 会刺激皮肤
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
H340 May cause genetic defects 可能导致遗传性缺陷
H350 May cause cancer 可能致癌
H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。

Safety Statements

S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签；
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；

Risk Statements

GHS Symbol

WGK Germany3

Hazard Codes T,N F;T;N T,N,F F,T,N

Packing GroupIII

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Hazard Class9

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {}

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 150 ug/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 72,733,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Musculoskeletal - tumors
REFERENCE :
   EXPTAX Experimentelle Pathologie (1967-1980).  (Jena, Ger. Dem. Rep.)
   V.1-18, 1967-80.  For publisher inform

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 39 mg/kg/6D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   29,506,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Brain and Coverings - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   29,1927,1969

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intrarenal
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   24,1969,1964

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,288,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 1 mg/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,4

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 147 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 109,183,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 200 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Fish - not otherwise specified Liver
DOSE/DURATION           : 20 nmol/L
REFERENCE :
   HKXUDL Huanjing Kexue Xuebao.  Environmental Sciences Journal.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1981-  Volume(issue)/page/year: 4,368,1984

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 3900 pmol/plate
REFERENCE :
   PPTCBY Proceedings of the International Symposium of the Princess Takamatsu
   Cancer Research Fund. (Japan Scientific Soc. Press, 6-2-10 Hongo, Bunkyo-ku,
   Tokyo 113, Japan)  1st-    1971-  Volume(issue)/pag

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 312 ng/plate
REFERENCE :
   RCOCB8 Research Communications in Chemic

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2 gm/kg
SEX/DURATION            : female 28 day(s) pre-mating
                          female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - stillbirth
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 20,224,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 150 mg/kg
SEX/DURATION            : female 6-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 42,195,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1344 mg/kg
SEX/DURATION            : female 15 day(s) pr

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2100 ug/kg
SEX/DURATION            : female 15-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   JDPHDH Journal of Developmental Physiology. (Oxford University Press,
   Pinkhill House, So

其他信息

用途一:本品在工业上无生产和使用价值，一般只作为生产过程中形成的副产物随废气排放。
刺激数据:皮肤-小鼠 0.014 毫克轻度
储运特性:通风低温干燥; 与库房食品原料分开存放
可燃性危险特性:可燃; 燃烧产生刺激烟雾
Alfa Aesar:苯并[a]芘,98% Benzo[a]pyrene, 96%(50-32-8)
外观性质:无色至淡黄色、针状、晶体(纯品)。
毒性分级:高毒
不溶于水，微溶于乙醇、甲醇，溶于苯、甲苯、二甲苯、氯仿、乙醚、丙酮等。
MSDS 信息:苯并(a)芘(50-32-8).msds
用途二:本品在工业上无生产和使用价值，一般只作为生产过程中形成的副产物随废气排放。校准仪器和装置；评价方法；工作标准；质量保证/质量控制；其他。
TCI Shanghai:3,4-苯并芘 3,4-Benzopyrene,>;95.0%(GC)(50-32-8)
图谱信息:苯并(a)芘(50-32-8)红外图谱(IR1) 苯并(a)芘(50-32-8)质谱(MS) 苯并(a)芘(50-32-8)核磁图( 1 HNMR)
Sigma Aldrich:50-32-8(sigmaaldrich)
MOL 文件:50-32-8.mol
职业标准:TWA 0.2 毫克/立方米
急性毒性:皮下-大鼠 LD50: 50 毫克/公斤; 腹腔-小鼠 LDL0: 500 毫克/公斤
苯并(a)芘价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 SB176001 苯并[a]芘 1g 2934元 2011/04/16 B0085 3,4-苯并芘 3,4-Benzopyrene 1G 2220元 2011/04/16 B0085 3,4-苯并芘 3,4-Benzopyrene 100MG 445元
灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
类别:有毒物品