Fmoc-Leu-OH 芴甲氧羰基-L-亮氨酸
CAS 35661-60-0 MFCD00037133
化学结构图
SMILES: CC(C)C[C@H](NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(O)=O
化学属性
| Mol. Formula | C21H23NO4 |
|---|---|
| Mol. Weight | 353 |
| Melting Point | 154.0 to 157.0 deg-C |
| TSCA | No |
| Density | 1.207 |
别名和识别编码
| Chemical Name | Fmoc-Leu-OH |
|---|---|
| Synonym | Fmoc-L-亮氨酸 Fmoc-Leu-OH N-(9-Fluorenylmethoxycarbonyl)-L-leucine N-(9-芴甲氧羰基)-L-亮氨酸 N-(9-芴甲氧羰基)-L-亮氨酸 Fmoc-L-亮氨酸 N-芴甲氧羰基-L-亮氨酸 |
| MDL Number | MFCD00037133 |
| PubChem Substance ID | 87570069 |
| Beilstein Registry Number | 2178254 |
| CAS Number | 35661-60-0 |
| EC Number | 252-662-7 |
| Reaxys-RN | 2178254 |
| Chemical Name Translation | 芴甲氧羰基-L-亮氨酸 |
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分类
- {SNA} Amino Acid Derivatives, Bioactive Small Molecules, Cell Biology, Chemical Biology, Chemical Synthesis, F, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids
- {SNA} Amino Acid Derivatives, Bioactive Small Molecules, Chemical Biology, Chemical Synthesis, F, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids,
- {SNA} Amino Acids & Derivatives, Catalysis and Inorganic Chemistry, Chemical Biology, Chemical Synthesis, Leucine, Peptide Chemistry, Standard Fmoc Amino Acids, The Yu MPAA Ligand Library
产品应用
- PPARγ的配体，诱导胰岛素的敏感性，而不是脂肪细胞分化
相关文献及参考
- Rocchi, S., et al., A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol. Cell. 8 , 737, (2001) 摘要
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
