N,O-Bis(Trimethylsilyl)Trifluoroacetamide N,O-双(三甲基硅烷基)三氟乙酰胺

CAS 25561-30-2 MFCD00008269

化学结构图

25561-30-2
SMILES: C[Si](C)(C)O/C(=N/[Si](C)(C)C)/C(F)(F)F

化学属性

Mol. FormulaC8H18F3NOSi2
Mol. Weight257
Boiling Point45-50
Refractive indexn20/D 1.384(lit.)
Density0.969
TSCAYes
Flash Point7°C(lit.)
Melting Point-10°
Stability易吸潮

别名和识别编码

Chemical NameN,O-Bis(Trimethylsilyl)Trifluoroacetamide
CAS Number25561-30-2
Alfabeta NameBISTRIMETHYLSILYLTRIFLUOROACETAMIDE NO()-,
MDL NumberMFCD00008269
Synonym BSTFA BSTFA + TMCS 硅烷化混合物 Fluka V N,O-双(三甲基硅)三氟乙酰胺(含三甲基氯硅烷) N,O-双(三甲基硅基)三氟乙酰胺 N,O-双(三甲基硅烷基)三氟乙酰胺
PubChem Substance ID87561074
Beilstein Registry Number2050024
Reaxys-RN3607620
EC Number247-103-9
Chemical Name TranslationN,O-双(三甲基硅烷基)三氟乙酰胺
InChIKeyXCOBLONWWXQEBS-UHFFFAOYSA-N
LabNetwork Molecule IDLN00118252
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分类

  • {SNA} β-Glucuronidase Drug Analysis Bundle, Analytical and Industrial Enzymes, BSTFA - N,O-Bis(trimethylsilyl)trifluoroacetamide, Biochemicals and Reagents, Chemical Synthesis, Derivatization agents, Enzymes, Inhibitors, and Substrates, Luminescent Compounds/Detection, Protecting and Derivatizing Reagents, Protection and Derivatization, Silicon-Based, Synthetic Reagents
  • {SNA} Carboxylic Acids, Derivatization Reagents, Derivatization Reagents GC, Derivatization agents, GC Derivatization Reagents, by Application, Reagents for Silylation, Silylation Reagents, 分析/色谱, 分析试剂, 发光化合物及其检测, 生化试剂
  • {SNA} Derivatization Reagents,
  • {SNA} Derivat
  • {SNA} Chemical Synthesis,

产品应用

  • 医药中间体。
  • 99%高纯级用在GC-MS系统分析食品中的糠醛含量。
  • 用于气相色谱的硅烷化试剂和衍生化试剂

相关文献及参考

  • Powerful silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions, similar to N,O-Bis(trimethyl­silyl)­acetamide, L00183, with the advantage that both the reagent and its by-product, trifluoroacetamide, are more volatile than the corresponding non-fluorinated analogues: Biochem. Biophys. Res. Commun., 31, 616 (1968). See Appendix 4.
  • Powerful silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions, similar to N,O-Bis(trimethyl­silyl)­acetamide, L00183, with the advantage that both the reagent and its by-product, trifluoroacetamide, are more volatile than the corresponding non-fluorinated analogues: Biochem. Biophys. Res. Commun., 31, 616 (1968). See Appendix 4.

安全信息

Warnings KEEP COLD, FLAMMABLE, CORROSIVE
GHS Symbol
WGK Germany3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 3 C
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331+P310
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P370+P378
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Storage condition Moisture Sensitive 0-10 充氩密封,储存温度:2-8°C。 0-10°C
UN Number 2924 UN2924
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S30 Never add water to this product 切勿将水加入该产品中;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S8 Keep container dry 保持容器干燥;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Risk Statements
  • R10 Flammable 易燃
  • R11 Highly flammable 非常易燃
  • R14 Reacts violently with water 遇水会猛烈反应
  • R34 Causes burns 会导致灼伤
  • R35 Causes severe burns 会导致严重灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Packing GroupIII
Hazard Class3/8

其他信息

  • 水中分解。

系列性分类


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