CAS 108-46-3 MFCD00002269-Resorcinol 间苯二酚 TAO{mole}

Resorcinol 间苯二酚

CAS 108-46-3 MFCD00002269

化学结构图

SMILES: OC1CCCC(O)C1

化学属性

Mol. Formula	C6H6O2
Mol. Weight	110.11
Boiling Point	-
Melting Point	109-111°C
Density	1.271
Flash Point	-
Solubility	Soluble in water (1000 mg/ml), DMSO, methanol, alcohol (111 mg/ml), and chloroform (slightly).,
TSCA	Yes
Autoignition Point	1126 °F
Vapor Density	3.8 (vs air)
Vapor Pressure	1 mmHg ( 21.1 °C)
Stability	对空气和光敏感

别名和识别编码

Chemical Name	Resorcinol
CAS Number	108-46-3
Synonym	Resorcinol {LY} Resorcinol {} {LY} Resorcinol {} {} {LY} Resorcinol {} {} {} {LY} Resorcinol {} {} {} {} {LY} Resorcinol {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Resorcinol {} {} {} {} {} {} {} {} {} {} {} {} {}
PubChem Substance ID	5054
EC Number	203-585-2
Beilstein Registry Number	6(2)802
MDL Number	-
Reaxys-RN	906905
Merck Number	8155
Chemical Name Translation	间苯二酚
Wiswesser Line Notation	QR CQ
LabNetwork Molecule ID	LN00196308
InChI	InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
Canonical SMILES	OC1=CC=CC(O)=C1

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品牌质保精细包装现货库存一流品牌服务

产品应用

An aromatic alcohol used as a chemical intermediate

安全信息

GHS Symbol

WGK Germany2

Hazard Codes Xn;N Xn,N

Hazard statements

H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H315 Causes skin irritation 会刺激皮肤
H318 Causes serious eye damage 严重伤害眼睛
H302 Harmful if swallowed 吞食有害
H319 Causes serious eye irritation 严重刺激眼睛
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
H370 Causes damage to organs 导致器官损伤
H301 Toxic if swallowed 吞食有毒

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

RTECSVG9625000

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P273 Avoid release to the environment. 避免释放到环境中。
P308+P311
P337+P313
P333+P313
P301+P312+P330
P302+P350
P305+P351+P338+P310
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P302+P352+P333+P313+P362+P364
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P301+P310+P330
P405 Store locked up. 上锁保管。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。

Signal word Danger

Safety Statements

S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S39 Wear eye/face protection 戴眼睛/面孔保护装置；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R50 Very toxic to aquatic organisms 对水生生物极毒
R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
R22 Harmful if swallowed 吞咽有害
R38 Irritating to skin 刺激皮肤
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

UN Number UN 2876 6.1/PG 3 2876

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store a

Packing GroupIII

Hazard Class6.1

Warnings 危化品目录(2015)

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4800 mg/kg/12W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   19,413,1959

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 166,437,1932

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJTOEX Japanese Journal of Toxicology. (Yakugyo Jihosha, Hokushin Bldg.,
   2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo, 101, Japan)  V.1-   1988-
   Volume(issue)/page/year: 4,105,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration o

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 213 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZGIMAL Z

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   63,47,1992

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 80 mg/L
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,533,1982

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 135,109,1984

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 40 mg/L
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,533,1982

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 1600 mg/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   14,251,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volu

Restrict 危险品

其他信息

上游原料:氢氧化钠 --> 盐酸 --> 硫酸 --> 苯 --> 发烟硫酸 --> 正丁醇 --> 3-
F:3-8-9-23
FEMA:3589
急性毒性:口服-大鼠LD50: 301 毫克/公斤;口服-小鼠LD50: 200 毫克/公斤
Acros Organics:间苯二酚 Resorcinol, 98%(108-46-3)
{Chemical
常规方法:用木桶内衬塑料袋包装，每桶重30
食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称允许使用该种添加剂的食品中文名称添加剂功能最大允许使用量（g/kg）最大允许残留量（g/kg）间苯二酚食品食品用香料用于配制香精的各香料成分不得超过在GB 2760中的最大允许使用量和最大允许残留量
方法二:1.苯磺酸用发烟硫酸磺化、中和，再经碱熔、酸化、正丁醇萃取、蒸去溶剂后，经蒸馏而得成品。2.由间二硝基苯加氢制得间苯二胺，再由间苯二胺水解制得。3.间氨基苯酚水解制得。间苯二酚也
所属类别一:农药中间体: 杀虫剂中间体: 有
可燃性危险特性:可燃; 燃烧产生有毒氯化物刺激烟雾
Resorcinol is an aromatic alcohol useful in the synthesis of pharmaceuticals and various organic compounds as a chemical intermediate. Resorcinol may be produced in bacteria from other phenolic compounds, and may undergo further conversion to alicyclic products and eventual oxidation to acetyl-CoA. Resorcinol cytotoxicity and cytokine release in human epidermal keratinocytes has been studied. Resorcinol is also used in platicizers and diazo dyes. It can be used in the qualitative determination of ketoses in the Seliwanoff test.。
{Chemicalb
{
下游产品:间亚苯基二苯甲酸酯 --> 荧光素 --> 异硫氰酸荧光素 --> 色甘酸钠 --> 乙胺香豆素盐酸盐 --> 2,4-二羟基苯甲酸 --> 8-乙酰基-7-羟基-4-甲基-2H-1-苯并吡喃-2-酮 --> 4-己基间苯二酚 --> 弱酸性红棕 V --> 5-氨基荧光素 --> 7-乙酰氧基-4-甲基香豆素 --> 丁苯吡胶乳 --> 酸性棕354 --> 3-氯-4-甲基-7-羟基香豆素 --> 3-乙氧基苯酚 --> 甲基伞形酮 --> 间羟基二苯胺 --> 1-[4-(苯甲酰氧基)-2-羟基苯基]-3-苯基-1,3-丙二酮 --> 酸性棕 75 --> 吲哚洛尔 --> 3-苄氧基苯酚 --> 1-[2,4-双(苯甲酰氧基)苯基]乙酮 --> 2',4'-二羟基苯己酮 --> 4-氧杂-4,5,
{C
MSDS 信息:间苯二酚(108-46-3).msds
所属类别二:食品添加剂: 食用香料（增香剂）: 天然等同香料和人造香
图谱信息:间苯二酚(108-46-3)红外图谱(IR1) 间苯二酚(108-46-3)红外图谱(IR2) 间苯二酚(108-46-3)质谱(MS) 间苯二酚(108-46-3)核磁图( 1 HNMR) 间苯二酚(108-46-3)核磁图( 13 CNMR)
使用限量:FEMA(mg/kg)：焙烤制品15.0；肉制品、汤料、调味品、肉羹，5.0；小吃食
Resorcinol is an aromatic alcohol useful in the synthesis of pharmaceuticals and various organic compound