• 原料直供
• 试剂商城
• 直接询价

分类

• {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
• {
• {SNA} Analytical Reagents, Analytical/Chromatography, Building Blocks, Chemical Synthesis, Derivatization Reagents, Derivatization Reagents HPLC,
• {SNA} Building Blocks, Chemical Synthesis, Derivatization Reagents, Derivatization Reagents HPLC, Nitro Compounds, Nitrogen Compounds, Organic Building Blocks, UV-VIS, 分析/色谱, 分析试剂
• {SA} Building Blocks, Chemical Synthesis, Nitro Compounds, Nitrogen Compounds, Organic Building Blocks
• {SNA} Building Blocks, Chemical Synthesis, Nitro Compounds, Nitrogen Compounds, Organic Building Blocks

产品应用

• 用作有机分析试剂及有机合成中间体，在医药工业中用于合成甲酰溶肉瘤素等药物。

相关文献及参考

• Beilstein:5,334
• Has been used as a protecting reagent for the carboxyl group in peptide synthesis: Helv. Chim. Acta, 42, 972 (1959); see 4-Nitrobenzyl­ chloride, A15749, and Appendix 6. Has also been used in ß-lactam synthesis. Cleavage by sodium sulfide avoids hydrogenolysis problems otherwise encountered with these sulfur-containing nuclei: J. Org. Chem., 43, 1243 (1978).
• Short: IV/1a
• Short: EINECS
• For the protection of alcohols, introduction of the group by the use of silver oxide has been recommended. Selective cleavage can be accomplished with DDQ (2,3-Dichloro-5,6-dicyanobenzoquinone, A11879) or by anodic oxidation. Many other benzyl-type protecting groups are unaffected by these conditions: Tetrahedron Lett., 31, 389 (1990). Indium metal in the presence of ammonium chloride is an effective deprotection system for 4-nitrobenzyl ethers and esters: J. Chem. Soc., Perkin 1, 955 (2001).

安全信息

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#07695

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 348,137,1995

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

其他信息

• Sigma Aldrich:100-11-8(sigmaaldrich)
• 图谱信息:对硝基溴化苄(100-11-8)核磁图( 13 CNMR) 对硝基溴化苄(100-11-8)核磁图( 1 HNMR) 对硝基溴化苄(100-11-8)Raman光谱 对硝基溴化苄(100-11-8)质谱(MS) 对硝基溴化苄(100-11-8)红外图谱(IR2) 对硝基溴化苄(100-11-8)红外图谱(IR1)
• 毒性分级:中毒
• 对硝基溴化苄价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80091214 4-硝基溴化苄;对硝基苄基溴; α-溴代对硝基甲苯; 对硝基溴化苄; 对硝基苯溴甲烷; 对硝基苯甲基溴 25g 99元 2011/04/16 N0181 4-硝基苄溴 4-Nitrobenzyl Bromide 500G 3370元 2011/04/16 N0181 4-硝基苄溴 4-Nitrobenzyl Bromide 25G 492元
• 上游原料:4-硝基甲苯
• F:10-19-21
• MSDS 信息:4-硝基溴化苄(100-11-8).msds
• 用途五:用作有机分析试剂及有机合成中间体，在医药工业中用于合成甲酰溶肉瘤素等药物。
• 类别:有毒物品
• 可燃性危险特性:明火可燃; 受热分解释出有毒溴化物和氮氧化物气体
• 燃烧(分解)产物:一氧化碳、二氧化碳、氧化氮、溴化氢。
• 不溶于水，溶于DMF、醋酸异丙酯和丙酮。
• 方法二:由对硝基甲苯溴化而得。
• Alfa Aesar:4-硝基溴苄,97+% 4-Nitrobenzyl bromide, 97+%(100-11-8)
• TCI Shanghai:4-硝基苄溴 4-Nitrobenzyl Bromide,>;98.0%(GC)(T)(100-11-8)
• 用途二:是有机合成原料及医药、染料中间体
• 海关编码:29049085
• 方法一:制备方法是由对硝基甲苯溴化，得到对硝基苄基溴。
• 包装:25KG纸板桶
• 灭火剂:二氧化碳、砂土、泡沫、雾状水
• 用途三:对硝基苄基溴又名对硝基溴苄、对硝基苯甲基溴，是一种有机合成中间体，在农药上用于合成杀虫剂氟环脲，此外也作为医药、染料中间体、通用试剂和有机分析试剂。
• 用途四:作用有机合成中间体，在医药工业中用于合成甲酰溶肉瘤素等药物。
• MOL 文件:100-11-8.mol
• 急性毒性:静注-小鼠 LD50: 56 毫克/立方米
• 储运特性:库房通风低温干燥; 与食品原料、氧化剂分开储运
• 下游产品:氟环脲 --> 4-吗啉甲基苯胺 --> 二乙基(4-硝基苯甲基)磷酸盐
• 外观:无色或浅黄色针状晶体，有催泪性
• 用途一:用作有机分析试剂及染料中间体
• Acros Organics:对硝基苄溴 4-Nitrobenzyl bromide, 99%(100-11-8)
• Hazard Note:Irritant/Corrosive