2-Bromoethanol 2-溴乙醇

CAS 540-51-2 MFCD00002827

化学结构图

540-51-2
SMILES: OCCBr

化学属性

Mol. FormulaC2
Mol. Weight125
Refractive index1.4880 to 1.4920
Density1.763
Flash Point>110°(230°F)
TSCAYes
Boiling Point56-57
Melting Point-80°C
Vapor Density4.3 (vs air)
Vapor Pressure2.4 mmHg ( 20 °C)
SolubilitySoluble in water
Stability对热、湿度及光敏感
pH:A

别名和识别编码

Chemical Name2-Bromoethanol
CAS Number540-51-2
EC Number208-748-1
Reaxys-RN878140
Merck Number3792
Beilstein Registry Number878140
PubChem Substance ID10898
MDL NumberMFCD00002827
Synonym -Bromoethylalcohol 1-Bromo-2-ethanol 1-Bromo-2-hydroxyethane 2-BROMOETHANOL, 1000MG, NEAT 2-Bromethanol 2-Bromo Ethenol 2-Bromoethanol 2-Bromoethyl alcohol 2-bromo-1-ethanol 2-bromoetanol 2-hydroxyethylbromide 2-溴乙醇 Bromoethanol CH2BrCH2OH(trans) ETHYLENE BROMOHYDRIN Ethanol, 2-bromo- Ethylenbromhydrin Ethylene bromohydrin Ethylene bromohydrin2-Hydroxyethyl bromide ethylene bromohydrine glycolbromohydrin Β-溴乙醇 亚乙基溴醇 亚乙基溴醇; 溴乙醇; 2-溴代乙醇 溴乙醇
Chemical Name Translation2-溴乙醇
Wiswesser Line NotationQ2E
LabNetwork Molecule IDLN00195719
InChIInChI=1S/C2H5BrO/c3-1-2-4/h4H,1-2H2
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Alcohols,
  • {SNA} A-B, Alpha Sort, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, B, BI - BZ, Bromo, Chemical Class,
  • {uni_hamburg} no charge; alcohol; 1fragment
  • A-B, ASTM 5578: Analysis of Ethylene Oxide in Air, ASTM Air Monitoring, Alpha Sort, Alphabetic, Analytical Standards, Analytical/Chromatography, B, BI - BZ, Bromo, Chemical Class, Chromatography, Environmental Standards, Halogenated, Method Specific, Volatiles/ Semivolatiles
  • {SNA} Alcohols,

产品应用

  • 可用于硝基芳烃(PcFe(II)/NaBH4/2-溴乙醇催化体系)的选择还原反应。

相关文献及参考

  • Carboxylic acids protected as their 2-bromoethyl esters are readily deprotected by cleavage with sodium trithiocarbonate: Synthesis, 715 (1974). 2-Bromoethyl esters of amino acids have been cleaved by conversion with NaI (Finkelstein) to the corresponding iodo esters, followed by reductive cleavage with Zn in DMF: Chem. Ber., 112, 2145 (1979); Angew. Chem. Int. Ed., 20, 894 (1981). See also Appendix 6.
  • Short: II/6
  • Merck:14,3792
  • Short: II/25B
  • Merck:14,3792 Beilstein:1,338

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H301+H311+H331
  • H227 Combustible liquid 可燃液体
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 8 T T,T+
RTECSKJ8225000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P330+P331+P310
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
UN Number 2922
Storage condition Light Sensitive & Hygroscopic <;0 储存温度2-8℃ Light Sensitive <0°C 2-8°C 避光保存
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R34 Causes burns 会导致灼伤
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S4 Keep away from living quarters 远离生活区;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Packing GroupII
Hazard Class8/6.1
Warnings 危化品目录(2015)
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,391,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 gm/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 2(2),246,1983

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,288,1972

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Klebsiella pneumoniae
DOSE/DURATION           : 15 mmol/L
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 25,85,1969

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 10 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,367,1974

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 20 uL/disc
REFERENCE :
   AEMIDF Applied and Environmental Microbiology.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.31-    1976-
   Volume(issue)/page/year: 43,177,1982

Restrict 危险品

其他信息

  • 灭火剂:泡沫、二氧化碳、砂土、雾状水
  • 不溶于水,能和乙醇、醚混溶,溶于除石油醚外的大多数有机溶剂。 C/20 mmHg
  • 下游产品:DL-氮杂环丁烷-2-羧酸 --> (S)-(-)-2-羧基环丁胺 --> 2-氨基乙基膦酸 --> 苯基乙烯基砜 --> 溴化乙酰胆碱 --> 甲基丙烯酸 2-(4-苯甲酰基-3-羟基苯氧基)乙酯 --> 2-丙烯酸 2-(4-苯甲酰-3-羟基苯氧基)乙基酯 --> HIDA --> 氯丙那林
  • 不溶于水,能和乙醇、醚混溶,溶于除石油醚外的大多数有机溶剂。
  • 类别:有毒物品
  • 2-溴乙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B0590 2-溴乙醇 2-Bromoethanol 25G 213元 2014/06/02 B0590 2-溴乙醇 2-Bromoethanol 500G 1540元 2010/06/21 106921000 2-溴乙醇 2-Bromoethanol 97% 100 ML 1880元
  • MSDS 信息:2-溴乙醇(540-51-2).msds
  • Sigma Aldrich:540-51-2(sigmaaldrich)
  • 蒸气密度:4.3 (vs air)
  • 储运特性:库房通风低温干燥; 与氧化剂、酸类、食品添加剂分开存放
  • 敏感性:Light Sensitive
  • 蒸气压:2.4 mm Hg ( 20 °C)
  • 用途一:用作溶剂、有机化工原料、分析试剂。
  • Alfa Aesar:2-溴乙醇,97% 2-Bromoethanol, 97%(540-51-2)
  • TCI Shanghai:2-溴乙醇 2-Bromoethanol,>;95.0%(GC)(540-51-2)
  • 方法一:由环氧乙烷与溴化氢反应而得:在0-20℃将环氧乙烷通入46%-48%的氢溴酸溶液中,通完后,反应1-2h。在10℃左右用碳酸钠中和氢溴酸,用乙醚提取2-溴乙醇,乙醚溶液用无水硫酸镁干燥过夜,过滤出干燥剂,回收乙醚后得粗品。经减压分馏而得成品。
  • 毒性分级:高毒
  • MOL 文件:540-51-2.mol
  • 外观性质:无色或浅黄色液体,其水溶液具有甜的焦灼味。
  • 可燃性危险特性:明火可燃; 高热放出有毒溴化物气体
  • 图谱信息:2-溴乙醇(540-51-2)红外图谱(IR1) 2-溴乙醇(540-51-2)红外图谱(IR2) 2-溴乙醇(540-51-2)核磁图( 1 HNMR) 2-溴乙醇(540-51-2)质谱(MS) 2-溴乙醇(540-51-2)核磁图( 13 CNMR)
  • Acros Organics:2-溴乙醇 2-Bromoethanol, 97%(540-51-2)
  • 上游原料:干燥剂
  • 急性毒性:腹腔- 小鼠 LDL0: 80 毫克/ 公斤

系列性分类