6,7-DIMETHYL-3-[[METHYL[2-[METHYL[[1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL]METHYL]AMINO]ETHYL]AMINO]METHYL]-(4H-1-BENZOPYRAN-4-ONE) DIHYDROCHLORIDE

CAS N/A MFCD09265259

化学结构图

N/A
SMILES: Cl.Cl.CC1=CC2OC=C(CN(C)CCN(C)CC3=CN(C4C=CC=CC3=4)C3=CC(=CC=C3)C(F)(F)F)C(=O)C=2C=C1C

化学属性

Mol. FormulaC32H32F3N3O2· 2HCl
Mol. Weight620.53

别名和识别编码

Chemical NameSPD304
Synonym 6,7-dimethyl-3-[[methyl[2-[methyl[[1-[3-(trifluoromethyl)phenyl]-1H-indol-3-yl]methyl]amino]ethyl]amino]methyl]-(4H-1-Benzopyran-4-one 二盐酸盐 6,7-dimethyl-3-[[methyl[2-[methyl[[1-[3-(trifluoromethyl)phenyl]-1H-indol-3-yl]methyl]amino]ethyl]amino]methyl]-(4H-1-Benzopyran-4-one 二盐酸盐 SPD00000304 SPD00000304
MDL NumberMFCD09265259
PubChem Substance ID24724602
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, S, TNF-α, Tumor Necrosis Factor (TNF) Superfamily
  • {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, S, TNF-α, Tumor Necrosis Factor (TNF) Superfamily
  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, S, TNF-α, Tumor Necrosis Factor (TNF) Superfamily, 生物活性小分子, 细胞信号转导和神经

相关文献及参考

  • He, M.M., et al., Small-molecule inhibition of TNF-α. Science 310 , 1022-1025, (2005) 摘要

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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