3,3'-Diaminobenzidine tetrahydrochloride 3,3'-二氨基联苯胺四盐酸盐

CAS N/A MFCD00012969

化学结构图

N/A
SMILES:

化学属性

Mol. Formula(NH2)2C6H3C6H3(NH2)2· 4HCl
Mol. Weight360.11
Melting Point280
SolubilitySoluble
Appearance tablets

别名和识别编码

Chemical Name3,3'-Diaminobenzidine tetrahydrochloride
MDL NumberMFCD00012969
PubChem Substance ID24893981
CAS Number7411-49-6
Synonym (1,1’-biphenyl)-3,3’,4,4’-tetramine,tetrahydrochloride (1,1’-联苯)-3,3’4,4’-四胺四盐酸盐 3,3',4,4'-BIPHENYLTETRAMINE TETRAHYDROCHLORIDE 3,3',4,4'-Biphenyltetramine tetrahydrochloride 3,3′,4,4′-四氨基联苯 四盐酸盐 DAB 3,3',4,4'-TETRAAMINOBIPHENYL TETRAHYDROCHLORIDE 3,3',4,4'-TETRAAMINODIPHENYL TETRAHYDROCHLORIDE 3,3',4,4'-Tetraaminobiphenyl tetrahydrochloride 3,3'-DIAMINOBENZIDINE HYDROCHLORIDE 3,3'-DIAMINOBENZIDINE TETRAHYDROCHLORIDE 3,3'-Diaminobenzidine (DAB) Liquid Substrate Dropper System 3,3'-Diaminobenzidine tetrahydrochloride 3,3'-二氨基联苯胺,盐酸盐 3,3'-二氨基联苯胺四盐酸盐 3,3,4,4-TETRAAMINOBIPHENYL TETRAHYDROCHLORIDE 3,3-DIAMINOBENZIDINE TETRAHYDROCHLORIDE 3,3-二氨基联苯胺盐酸盐(硒试剂DAB) 3,3-对二氨基联苯四盐酸盐 3,3`,4,4`-四氨基联苯,四盐酸 3,3ˊ-二氨基联苯胺盐酸盐(二水) 3,3’-二氨基联苯胺盐酸 3,3’-二氨基联苯胺盐酸盐 3,3′,4,4′-Tetraamindiphenyl tetrahydrochloride 3,3′-Diaminobenzidine hydrochlride 3,3′-二氨基联苯胺盐酸 3,4,3',4'-TETRA-AMINOBIPHENYL HYDROCHLORIDE 3,4,3ˊ,4ˊ-四氨基联苯四盐酸盐 3,4,3’,4’-四氨基联苯盐酸 3,4,3′,4′-四氨基联苯盐酸 DAB DAB 4HCL DAB PEROXIDASE SUBSTRATE DAB SUBSTRATE DAB TABLET DAB TETRAHYDROCHLORIDE DAB WITH METAL ENHANCER DAB-HCL DIAMINOBENZIDINE, TETRAHYDROCHLORIDE 盐酸-3,3ˊ-二氨基联苯胺 盐酸-3,3’-二氨基联苯胺 盐酸-3,3′-二氨基联苯胺 硒试剂
Beilstein Registry Number1212988
EC Number231-018-9
Chemical Name Translation3,3'-二氨基联苯胺四盐酸盐
Wiswesser Line NotationZR BZ DR CZ DZ &GH 4
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分类

  • {SNA} Alphabetical Listing, Antibodies, Biochemicals and Reagents, Blotting/Histochemistry Substrates,
  • {SNA} Alphabetical Listing, Biochemicals and Reagents, Blotting/Histochemistry Substrates, Detection Substrates, Enzyme Substrates, Immunohistochemistry, Liquid Substrate Systems, Peroxidase, Substrates for Peroxidase, Substrates, Buffers & Blockers, 抗体, 辅助产品, 酶、抑制剂和底物
  • {SNA} Alphabetical Listing, Colorimetric, Core Bioreagents, Detection, Detection Substrates, Enzyme Substrates, General Reagents, Immunohistochemistry, Life Science Reagents

相关文献及参考

  • Hsu SM, Soban E., Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry. J. Histochem. Cytochem. 30 , 1079-1082, (1982) 摘要
  • Chu NM, Janckila AJ, Wallace JH, Yam LT., Assessment of a method for immunochemical detection of antigen on nitrocellulose membranes. J. Histochem. Cytochem. 37 , 257-263, (1989) 摘要
  • Damen CW, Speijer H, Hermens WT, et. al., The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry. Anal. Biochem. 393 , 73-79, (2009) 摘要

安全信息

Hazard Codes F,T T
Hazard statements
  • H350 May cause cancer 可能致癌
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
GHS Symbol
WGK Germany3
Precautionary statements
  • P308+P313
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P337+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P301+P312+P330
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
RTECSDV8753000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Danger
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S22 Do not breathe dust 不要吸入粉尘；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S24 Avoid contact with skin 避免皮肤接触；
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
  • R45 May cause cancer 可能致癌
Storage condition 2-8°C
UN Number UN 3316 9/PG 2
Warnings 危化品目录(2015) 危险化学品 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 260 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 520 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JEPTDQ Journal of Environmental Pathology and Toxicology.  (Park Forest
   South, IL)  V.1-5(3), 1977-81(?).  For publisher information, see JEPOEC.
   Volume(issue)/page/year: 2(2),325,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the
   National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial
   Ave., Cambridge, MA 02141)  Volume(issue)/page/year: NCI-E-68-1311,1973

其他信息

  • 可燃性危险特性:可燃; 燃烧产生有毒氮氧化物和氯化氢烟雾
  • 毒性分级:高毒
  • MOL 文件:7411-49-6.mol
  • Acros Organics:3,3-二氨基联苯胺盐酸盐(硒试剂DAB) DAB EASYtablets, for immunoblotting, 10 mg/tablet(7411-49-6)
  • 类别:有毒物品
  • 敏感性:Moisture Sensitive/Air Sensitive
  • MSDS 信息:3,3',4,4'-Biphenyltetramine tetrahydrochloride(7411-49-6).msds
  • Sigma Aldrich:7411-49-6(sigmaaldrich)
  • 用途二:是诊断用试剂
  • F:3-8-10
  • 储运特性:库房通风低温干燥; 与食品原料分开存放
  • 用途一:用作分析试剂
  • 图谱信息:3,3'-二氨基联苯胺四盐酸盐(7411-49-6)红外图谱(IR1)
  • 3,3'-二氨基联苯胺四盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80042623 3，3-二氨基联苯胺盐酸盐 10g 80元 2011/08/23 xw020010 3,3’-二氨基联苯胺盐酸盐（DAB） 1g 75元 2010/06/21 328005000 3,3'-二氨基联苯胺四盐酸盐 DAB EASY tablets , for immunohistochemistry, 10 mg/tablet 500 MG 1777元
  • 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
  • 急性毒性:腹腔-小鼠 LD50: 330 毫克/公斤

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Fluorescent Enzyme Substrates - Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Enzyme Substrates for Electrophoresis - Fluorescent Enzyme Substrates
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Inorganic Salts - Synthetic Reagents
  4. Ammonium - Inorganic Salts
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amine Salts - Nitrogen Compounds
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Detection Substrates - Enzyme Substrates
  6. Immunohistochemistry - Detection Substrates
  7. Peroxidase - Immunohistochemistry
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Peroxidase Substrates - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Detection Substrates - Enzyme Substrates
  6. Western Blotting - Detection Substrates
  7. Peroxidase - Western Blotting
  1. Life Science 生命科学
  2. Antibodies (Primary & Secondary) 抗体
  3. Supplementary Products - Antibodies
  4. Substrates, Buffers & Blockers - Supplementary Products
  5. Substrates for Peroxidase - Substrates, Buffers & Blockers
  6. Blotting/Histochemistry Substrates - Substrates for Peroxidase
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Detection Substrates - Enzyme Substrates
  6. Western Blotting - Detection Substrates
  7. Peroxidase - Western Blotting
  8. Powders - Peroxidase
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Detection Substrates - Enzyme Substrates
  6. Immunohistochemistry - Detection Substrates
  7. Peroxidase - Immunohistochemistry
  8. Liquid Substrate Systems - Peroxidase
  1. Analytical & Chromatography 分析化学与色谱
  2. HPLC
  3. Analytical Reagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Fluorescent Enzyme Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Detection Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Fluorescent Probes, Labels, Particles and Stains
  4. Fluorescent Enzyme Substrates
  5. Fluorescent Enzyme Substrates for Immunoassays
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Biochemicals and Reagents
  4. Stains and Dyes
  5. Natural Dyes
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Detection Substrates
  6. ELISA Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Substrates
  5. Substrates by Enzyme
  6. Oxaloacetate decarboxylase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Analytical Enzymes
  5. Peroxidase Enzymes and Reagents
  6. Peroxidase Inhibitors
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Enzyme Substrates
  6. Alphabetical
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Luminescent Compounds/Detection
  4. Fluorescent Probes, Labels, Particles and Stains
  5. Fluorescent Enzyme Substrates
  6. Fluorescent Enzyme Substrates for Immunoassays

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