四氧嘧啶 一水合物 四氧嘧啶 一水合物

CAS N/A MFCD00006031

化学结构图

N/A
SMILES:

化学属性

Mol. FormulaC4H2N2O4·H2O
Mol. Weight160.09
Melting Point~245 °C (dec.)

别名和识别编码

Chemical NamePyrimidine-2,4,5,6(1H,3H)-tetraone monohydrate
CAS Number50-71-5
Reaxys-RN132451
Beilstein Registry Number24(3/4)2137
PubChem Substance ID87561880
MDL NumberMFCD00006031
Merck Number282
Synonym Mesoxalylcarbamide AlloxanTetrahydrate99% 四氧嘧啶 MESOXALYLUREA 2,4,5,6(1H,3H)-PYRIMIDINETETRONE 2,4,5,6-Pyrimidintetrone 2,4,5,6-Tetraoxohexahydropyrimidine 四氧嘧啶,四水 Mesoxalylurea Alloxane yrimidinetetrone 2,4,5,6-pyrimidintetron Alloxan 7169 MESOXALYLUREA 98% MESOXALYLCARBAMIDE 98% 阿脲,四氧嘧啶 5-oxo-barbituricaci Barbituric acid, 5-oxo- 2,4,5,6-Pyrimidintetron 2,4,5,6(1H,3H)-Pyrimidinetetrone ALLOXAN 98% ALLOXAN 阿脲 Urea, mesoxalyl- ,4,5,6-Pyrimidinetetrone MESOXALYLCARBAMIDE ALLOXAN 4-HYDRATE Alloxan(Hydrate)
EC Number200-062-0
Chemical Name Translation四氧嘧啶 一水合物
Wiswesser Line NotationT6MVMVVVJ
LabNetwork Molecule IDLN00200981
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安全信息

RTECSUW0492000
Storage condition 0-10 0-10°C 2-8°C
Signal word
Hazard statements
  • H302+H312+H332
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P312+P362+P364
  • P304+P340+P312
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard Codes Xn
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
WGK Germany3
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,862,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 5,6,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 142,1335,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co.,
   1956-59  Volume(issue)/page/year: 5,6,1959

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Rectal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - change

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
REFERENCE :
   JOHEA8 Journal of Heredity.  (American Genetic Assoc., 818 18th St., NW,
   Washington, DC 20006) V.5-    1914-  Volume(issue)/page/year: 65,345,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 155 mg/kg
SEX/DURATION            : female 15-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - skin and skin
   appendages
REFERENCE :
   JDREAF Journal of Dental Research.  (International Assoc. for Dental
   Research, 734 15th St., NW, Suite 809, Washington, DC 20005)  V.1-    1919-
   Volume(issue)/page/year: 32,246,1953

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 200 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   JEEMAF Journal of Embryology and Experimental Morphology.  (Essex, UK)
   V.1-98, 1953-86. For Publisher information, see DEVPED
   Volume(issue)/page/year: 14,63,1965

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 60 mg/kg
SEX/DURATION            : lactating female 1 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Maternal Effects - postpartum
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Mammal - pig
DOSE                    : 50 mg/kg
SEX/DURATION            : female 75 day(s) after conception
TOXI

其他信息

  • 储运特性:库房通风低温干燥; 与食品原料分开存放; 勿存放于密封罐内
  • 类别:农药
  • 爆炸物危险特性:可爆; 加热超过170℃即发生爆炸
  • 毒性分级:中毒
  • 刺激数据:眼睛-兔子 500 毫克/24小时 轻度
  • 可燃性危险特性:可燃; 常温即分解二氧化碳; 燃烧产生有毒氮氧化物烟雾
  • 下游产品:维生素 B2 --> 核黄酸
  • MSDS 信息:Alloxan(50-71-5).msds
  • 灭火剂:干粉、泡沫、砂土、二氧化碳, 雾状水
  • F:8-10-23
  • 急性毒性:口服-大鼠 LD50: 5210 毫克/公斤; 腹腔-小鼠LDL0:300 毫克/公斤
  • MOL 文件:50-71-5.mol
  • Sigma Aldrich:50-71-5(sigmaaldrich)

系列性分类


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