委托采购
结构式检索
MolSoft

Ketcher

ChemDraw

同时返回精确结构检索、子结构（亚结构）检索、相似结构检索结果。

同时返回精确结构检索、子结构（亚结构）检索、相似结构检索结果。

同时返回精确结构检索、子结构（亚结构）检索、相似结构检索结果。

显示chemdraw
供应商合作与认证
TAO{mole}精选
分类目录
登陆/注册

PDGFR

下级目录

AAL-993

N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide

AZD-2932

Axitinib

目录项下的产品

269390-77-4

269390-77-4 / MFCD69390774
AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM).

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

850879-09-3

850879-09-3 / MFCD50879093
N-(Benzo[D][1,3]Dioxol-5-Ylmethyl)-4-(Benzofuro[3,2-d]Pyrimidin-4-Yl)Piperazine-1-Carbothioamide
N-(苯并[d][1,3]二氧杂环戊烷-5-基甲基)-4-(苯并呋喃并[3,2-d]嘧啶-4-基)哌嗪-1-甲硫酰胺

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

883986-34-3

883986-34-3 / MFCD83986343
AZD-2932 is a high affinity inhibitor of VEFGR-2 and PDGFR. AZD-2932 has a balanced ~ 1:1 ratio of activity vs both VEGFR-2 and PDGFRβ and shows IC50 values of 8 and 4 nM against the two enzymes, respectively. It is also active on c-Kit and FLT3 with good selectivity on a panel of kinases. The pharmacokinetic behavior and the preclinical antitumor activity in nude mice bearing C6 rat glial tumors indicate that 31 has the potential to become an antiangiogenic agent in the clinic.

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

319460-85-0

319460-85-0 / MFCD09837898
Axitinib
阿西替尼

原料 0 ^资源 0.0^询 0.0^%成交 ^交易量
试剂

中华人民共和国
√