PF-3644022 hydrate
CAS N/A MFCD21363374
化学结构图
SMILES:
化学属性
| Mol. Weight | 374.46 (anhydrous basis) |
|---|---|
| Mol. Formula | C21H18N4OS · xH2O |
别名和识别编码
| Synonym | (10R)-9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5′,6′:4,5]thieno[3,2-f]quinolin-8-one hydrate (10R)-9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one hydrate |
|---|---|
| MDL Number | MFCD21363374 |
| Chemical Name | PF-3644022 hydrate |
| PubChem Substance ID | 329823762 |
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分类
- Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, MAPK-Activated Protein Kinase (MAPKAP Kinase), P, Pfizer Compounds, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Ind
相关文献及参考
- Mourey RJ, Burnette BL, et al., A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation. J. Pharmacol. Exp. Ther. 3 , 797-807, (2010)
安全信息
GHS Symbol
- P305+P351+P338
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
- R22 Harmful if swallowed 吞咽有害
