Teijin compound 1 hydrochloride
CAS N/A MFCD16618399
化学结构图
SMILES:
化学属性
| Mol. Weight | 476.32 |
|---|---|
| Mol. Formula | C21H21ClF3N3O2·HCl |
别名和识别编码
| Synonym | N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide hydrochloride |
|---|---|
| MDL Number | MFCD16618399 |
| Chemical Name | Teijin compound 1 hydrochloride |
| PubChem Substance ID | 329826865 |
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分类
- {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, T
- {SNA} Bioactive Small Molecule Alphabetical Index, Chemokine Inhibitors, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, T, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- Hall, S.E., et al., Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol. Pharmacol. 75 , 1325-1336, (2009) 摘要
- Moree, W. J., et al., Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series Bioorg. Med. Chem. Lett. 18 , 1869-1873, (2008)
- Moree, W.J., et al., Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivatives. Bioorg. Med. Chem. Lett. 14th ed.,, 5413-5416, (2004)
