CAS 20350-15-6 MFCD00083258-Brefeldin A 布雷非德菌素 A TAO{mole}

Brefeldin A 布雷非德菌素 A

CAS 20350-15-6 MFCD00083258

化学结构图

SMILES: C[C@H]1CCCC=C[C@@H]2C[C@H](O)C[C@H]2[C@H](O)C=CC(=O)O1

化学属性

Mol. Formula	C16
Mol. Weight	280
Flash Point	87 ºC
Melting Point	204-205

别名和识别编码

Chemical Name	Brefeldin A
CAS Number	20350-15-6
Synonym	Cyanein NSC 244390 Decumbin Ascotoxin ?-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ?-Lactone, BFA, Cyanein, Ascotoxin, Decumbin Cyanaein Brefeldin A Nectrolide γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid NSC 56310 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent [f]oxacyclotridecin-4-one; Ascotoxin; Cyanein (+)-Brefeldin A
MDL Number	MFCD00083258
InChIKey	KQNZDYYTLMIZCT-KQPMLPITSA-N
Chemical Name Translation	布雷非德菌素 A
Wiswesser Line Notation	T5-13- IVO GU OUTJ CQ FQ K1
Beilstein Registry Number	25191

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

A macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.

安全信息

Safety Statements

Risk Statements

R25 Toxic if swallowed 吞咽有毒

RTECSGY8410000

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJANAX Japanese Journal of Antibiotics.  (Japan Antibiotics Research Assoc.,
   2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan)  V.21-    1968-
   Volume(issue)/page/year: 34,51,1981

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 200 ug/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 39,1148,1986

GHS Symbol

UN Number

Hazard Codes

Signal word

WGK Germany3

Precautionary statements

Packing GroupIII