7-FLUORO-4-HYDROXY-2H-CHROMEN-2-ONE

CAS N/A MFCD11845381

化学结构图

N/A
SMILES: OC1=CC(=O)OC2C=C(F)C=CC=21

化学属性

Mol. FormulaC9H5FO3
Mol. Weight180.13
Melting Point220-225 °C

别名和识别编码

Chemical Name7-FLUORO-4-HYDROXY-2H-CHROMEN-2-ONE
Synonym 7-Fluoro-4-hydroxy-1(2H)-benzopyran-2-one 7-Fluoro-4-hydroxy-2H-chromen-2-one
MDL NumberMFCD11845381
CAS Number2145-27-9
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分类

  • Building Blocks, Chemical Synthesis, Chromanes/Chromenes, Fluorinated Building Blocks, Heterocyclic Fluorinated Building Blocks, Other Fluorinated Heterocycles

相关文献及参考

  • 1. Zhu, X.; et al., Enantioselective Synthesis of Polycyclic Coumarin Derivatives Catalyzed by an in Situ Formed Primary Amine-Imine Catalyst Org. Lett. 13 , 4382-4385, (2011)
  • 2. Nolan, K. A.; et al., Synthesis and Biological Evaluation of Coumarin-Based Inhibitors of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) J. Med. Chem. 52 , 7142-7156, (2009)
  • 3. Halland, N.; et al., Organocatalytic asymmetric Michael reaction of cyclic 1,3-dicarbonyl compounds and α,β-unsaturated ketones - A highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant Angew. Chem. Int. Ed. Engl. 42 , 4955-4957, (2003)
  • 4. Halland, N.; et al., Direct Asymmetric Michael Reactions of Cyclic 1,3-Dicarbonyl Compounds and Enamines Catalyzed by Chiral Bisoxazoline-Copper(II) Complexes J. Org. Chem. 68 , 5067-5074, (2003)

安全信息

GHS Symbol
WGK Germany3
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害

系列性分类


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