2-(Morpholinomethyl)-5-((5-((7-(Trifluoromethyl)Quinolin-4-Yl)Thio)Pentyl)Oxy)-4H-Pyran-4-One Dihydrochloride 2-(吗啉-4-基甲基)-5-((5-((7-(三氟甲基)喹啉-4-基)硫基)戊基)氧基)-4H-吡喃-4-酮二盐酸盐
CAS 754240-09-0 MFCD11114384
化学结构图
SMILES: Cl.Cl.O=C1C=C(CN2CCOCC2)OC=C1OCCCCCSC1=CC=NC2C=C(C=CC=21)C(F)(F)F
化学属性
| Mol. Formula | C25H29Cl2F3N2O4S |
|---|---|
| Mol. Weight | 581 |
别名和识别编码
| Chemical Name | 2-(Morpholinomethyl)-5-((5-((7-(Trifluoromethyl)Quinolin-4-Yl)Thio)Pentyl)Oxy)-4H-Pyran-4-One Dihydrochloride |
|---|---|
| Synonym | 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride EHT 1864 |
| MDL Number | MFCD11114384 |
| PubChem Substance ID | 329799014 |
| CAS Number | 754240-09-0 |
| Chemical Name Translation | 2-(吗啉-4-基甲基)-5-((5-((7-(三氟甲基)喹啉-4-基)硫基)戊基)氧基)-4H-吡喃-4-酮二盐酸盐 |
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分类
- {SNA} Bioactive Small Molecules, Cell Biology, E
- {SNA} Bioactive Small Molecule Alphabetical Index, E, 生物活性小分子, 细胞生物学
相关文献及参考
- [2]. Shutes A, et al. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. J Biol Chem. 2007 Dec 7;282(49):35666-78.
- [3]. Onesto C, et al. Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. Methods Enzymol. 2008;439:111-29.
- [1]. Desire L, et al. RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. J Biol Chem. 2005 Nov 11;280(45):37516-25.
- [1]. Desire L, et al. RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo. J Biol Chem. 2005 Nov 11;280(45):37516-25.
- [2]. Shutes A, et al. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. J Biol Chem. 2007 Dec 7;282(49):35666-78.
- [3]. Onesto C, et al. Characterization of EHT 1864, a n
