3-METHYL-5-[(2S)-1-METHYL-2-PYRROLIDINYL]ISOXAZOLE HYDROCHLORIDE
CAS 147388-83-8 MFCD11045960
化学结构图
SMILES: Cl.CC1C=C(ON=1)[C@@H]1CCCN1C
化学属性
| Mol. Formula | C9H14N2O · HCl |
|---|---|
| Mol. Weight | 202.68 |
别名和识别编码
| Chemical Name | ABT-418 hydrochloride |
|---|---|
| Synonym | 3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride |
| MDL Number | MFCD11045960 |
| PubChem Substance ID | 24724395 |
| CAS Number | 147388-83-8 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} A-AM, Abbott, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Cholinergics, Diversification Ready Pharma-Developed Compounds, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Nicotinic Acetylcholine Receptor Modulators, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- A-AM, Abbott, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, Ion Channels,
相关文献及参考
- Brioni, J.D., et al., Anxiolytic-like effects of the novel cholinergic channel activator ABT-418 J. Pharmacol. Exp. Ther. 271 , 353-61, (1994)
- Brioni, J.D., et al., ABT-418: discriminative stimulus properties and effect on ventral tegmental cell activity Psychopharmacology 119 , 368-75, (1995)
- Nikolov, R., Alzheimer's disease therapy - an update Drug News Perspect. 11 , 248-55, (1998)
- Papke, R.L. et al. Br. J. Pharmacol. 120 , 429-438, (1997)
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P301+P310
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P302+P350
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- H330 Fatal if inhaled 吸入致命
- H310 Fatal in contact with skin 皮肤接触致命
- H300 Fatal if swallowed 吞食致命
- S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭，置于通风良好的场所；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S22 Do not breathe dust 不要吸入粉尘；
- R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
