4-[5-[(2-ETHOXY-5-PYRIMIDINYL)METHYL]-2-[[(4-FLUOROPHENYL)METHYL]THIO]-4-OXO-1(4H)-PYRIMIDINYL]-BENZOIC ACID ETHYL ESTER
CAS 306974-70-9 MFCD09953714
化学结构图
SMILES: CCOC1N=CC(CC2=CN(C(=NC2=O)SCC2C=CC(F)=CC=2)C2C=CC(=CC=2)C(=O)OCC)=CN=1
化学属性
| Mol. Formula | C27H25FN4O4S |
|---|---|
| Mol. Weight | 520.583 |
别名和识别编码
| Chemical Name | 4-[5-[(2-ETHOXY-5-PYRIMIDINYL)METHYL]-2-[[(4-FLUOROPHENYL)METHYL]THIO]-4-OXO-1(4H)-PYRIMIDINYL]-BENZOIC ACID ETHYL ESTER |
|---|---|
| Chemical Name Translation |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
相关文献及参考
- [2]. Briscoe CP, et al. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol. 2006 Jul;148(5):619-28.
- [3]. Manosalva C, et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. PLoS One. 2015 Mar 19;10(3):e0119715.
- [4]. Nakamoto K, et al. Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatorychronic pain. PLoS One. 2013 Dec 12;8(12):e81563.
- [1]. Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent
- [1]. Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist. Mol Pharmacol. 2007 Apr;71(
