Tolvaptan 托伐普坦

CAS 150683-30-0 MFCD09837707

化学结构图

150683-30-0
SMILES: CC1=CC(=CC=C1C(=O)N1CCC[C@@H](O)C2C=C(Cl)C=CC1=2)NC(=O)C1=CC=CC=C1C

化学属性

Mol. FormulaC26H25ClN2O3
Mol. Weight448.948

别名和识别编码

Chemical NameTolvaptan
LabNetwork Molecule IDLN01374893
Chemical Name Translation托伐普坦
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相关文献及参考

  • [2]. Inomata T.
  • [3]. Vaduganathan M, Gheorghiade M, Pang PS, Konstam MA, Zannad F, Swedberg K, Grinfeld L, Burnett JC Jr, Krasa HB, Zimmer C, Blair J, Ouyang J, Maggioni AP; EVEREST investigators.
  • [4]. Y Yamamura et al. OPC-41061, a Highly Potent Human Vasopressin V2-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats. J. Pharmacol.
  • [5]. RW Schrier et al. Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia. N Engl J Med 2006, 355, 2099-2112.
  • Efficacy of oral tolvaptan in acute heart failure patients with hypotension and renal impairment.
  • Efficacy of oral tolvaptan in acute heart failure patients with hypotension and renal impairment.
  • Exp. Ther. 1998, 287(3), 860-867.
  • Exp. Ther. 1998, 287(3), 860-867.
  • Hyponatremia in critical care patients: Frequency, outcome, characteristics, and treatment with the vasopressin V(2)-receptor an

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