Cambinol 5-[(2-羟基萘-1-基)甲基]-6-苯基-2-硫代-2,3-二氢嘧啶-4(1H)-酮
CAS 14513-15-6 MFCD09057543
化学结构图
SMILES: OC1C=CC2=CC=CC=C2C=1CC1C(=O)NC(=S)NC=1C1C=CC=CC=1
化学属性
| Mol. Formula | C21H16N2O2S |
|---|---|
| Mol. Weight | 360.43 |
别名和识别编码
| Chemical Name | Cambinol |
|---|---|
| Synonym | 5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 5-[(2-hydroxy-1-naphthyl)methyl]-2-mercapto-6-phenyl-4(3H)-Pyrimidinone NSC-1125476 Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone 5-[(2-hydroxy-1-naphthyl)methyl]-2-mercapto-6-phenyl-4(3H)-Pyrimidinone Cambinol NSC-1125476 Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone |
| MDL Number | MFCD09057543 |
| PubChem Substance ID | 329774799 |
| CAS Number | 14513-15-6 |
| Chemical Name Translation | 5-[(2-羟基萘-1-基)甲基]-6-苯基-2-硫代-2,3-二氢嘧啶-4(1H)-酮 |
| Reaxys-RN | 1599964 |
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专业采购外包团队在线服务
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分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules for Epigenetic Research, C-CH, Gene Regulation, Gene Regulation and Expression, Histone Deacetylase Inhibitors, Other HDAC Inhibitors, 分子生物学, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 表观遗传学
- {SNA} Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, C-CH, Cell Biology, Cell Signaling and Neuroscience, Epigenetics, Gene Regulation, Gene Regulation and Expression, Histone Deacetylase Inhibitors, Molecular Biology, Other HDAC Inhibitors
相关文献及参考
- [2]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
- [1]. Heltweg B, et al. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006 Apr 15;66(8):4368-77.
- [1]. Heltweg B, et al. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006 Apr 15;66(8):4368-77.
- [2]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
安全信息
GHS Symbol
- P305+P351+P338
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- R22 Harmful if swallowed 吞咽有害
