4-(2-CHLOROPHENYL)-1-ETHYL-1,4-DIHYDRO-6-METHYL-2,3,5-PYRIDINETRICARBOXYLIC ACID 5-ISOPROPYL ESTER DISODIUM SALT HYDRATE
CAS 114290-51-6 MFCD08705410
化学结构图
SMILES:
化学属性
| Mol. Formula | C20H20ClNNa2O6· xH2O |
|---|---|
| Mol. Weight | 451.81 (anhydrous basis) |
别名和识别编码
| Chemical Name | BAY U6751 hydrate |
|---|---|
| Synonym | 4-(2-Chlorophenyl)-1-ethyl-1,4-dihydro-6-methyl-2,3,5-pyridinetricarboxylic acid 5-isopropyl ester disodium salt hydrate |
| MDL Number | MFCD08705410 |
| PubChem Substance ID | 24891730 |
| CAS Number | 114290-51-6 (anhydrous) |
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分类
- Approved Therapeutics/Drug Candidates, B, Bayer, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors
- {SNA} Approved Therapeutics/Drug Candidates, B, Bayer, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, Tyrosine Phosphatase (TP), Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, B,
相关文献及参考
- Bergans, N., et al. , Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite. Diabetes 49 , 1419-1426, (2000)
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
