AMN082
CAS 97075-46-2 MFCD08702723
化学结构图
SMILES:
化学属性
| Mol. Formula | C28H28N2· 2HCl |
|---|---|
| Mol. Weight | 465.46 |
别名和识别编码
| Chemical Name | AMN082 |
|---|---|
| Synonym | N,N′-Dibenzhydrylethane-1,2-diamine dihydrochloride N,N'-Dibenzhydrylethane-1,2-diamine dihydrochloride AMN082 |
| MDL Number | MFCD08702723 |
| PubChem Substance ID | 24891112 |
| Chemical Name Translation |
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分类
- {SNA} A-AM, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Metabotropic Agonists, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
- {SNA} Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Metabotropic Agonists, Neuroscience, Neurotransmission, Neur
相关文献及参考
- [2]. Wang CC, et al. Metabotropic glutamate 7 receptor agonist AMN082 inhibits glutamate release in rat cerebral cortex nerve terminal. Eur J Pharmacol. 2018;823:11-18.
- [3]. Jenda M, et al. AMN082, a metabotropic glutamate receptor 7 allosteric agonist, attenuates locomotor sensitization and cross-sensitization induced by cocaine and morphine in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2015;57:166-175.
- [1]. Mitsukawa K, et al. A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo. Proc Natl Acad Sci U S A. 2005;102(51):18712-18717.
- [1]. Mitsukawa K, et al. A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo. Proc Natl Acad Sci U S A. 2005;102(51):18712-18717.
- [2]. Wang CC, et al. Metabotropic glutamate 7 receptor agonist AMN082 inhibits glutamate rele
安全信息
GHS Symbol
- P273 Avoid release to the environment. 避免释放到环境中。
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H302 Harmful if swallowed 吞食有害
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- R50 Very toxic to aquatic organisms 对水生生物极毒
- R22 Harmful if swallowed 吞咽有害
