1-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-3,3-Dimethylindolin-2-One Hydrochloride 1-(2-(4-(4-氟苯甲酰基)哌啶-1-基)乙基)-3,3-二甲基吲哚啉-2-酮盐酸盐
CAS 192927-92-7 MFCD07772272
化学结构图
SMILES: Cl.CC1(C)C2C=CC=CC=2N(CCN2CCC(CC2)C(=O)C2C=CC(F)=CC=2)C1=O
化学属性
| Mol. Formula | C24H27O2N2F · HCl |
|---|---|
| Mol. Weight | 430.94 |
别名和识别编码
| Chemical Name | 1-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-3,3-Dimethylindolin-2-One Hydrochloride |
|---|---|
| Synonym | 3,3-Dimethyl-1-{2-[4-(4-fluorobenzoyl)-1-piperidinyl]-1-ethyl}-1,3-dihydro-2H-indol-2-one hydrochloride LY-310,762 hydrochloride |
| MDL Number | MFCD07772272 |
| PubChem Substance ID | 24278114 |
| Chemical Name Translation | 1-(2-(4-(4-氟苯甲酰基)哌啶-1-基)乙基)-3,3-二甲基吲哚啉-2-酮盐酸盐 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Eli Lilly, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Serotonergics, Serotonergics - Antagonists, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Eli Lilly, GPCR Modulators, GPCR Proteins, Modulators and Antibodies,
相关文献及参考
- [2]. Choi IS, et al. 5-HT(1B) receptors inhibit glutamate release from primary afferent terminals in rat medullary dorsal horn neurons. Br J Pharmacol, 2012,167(2), 356-367.
- [1]. Pullar IA, et al. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur J Pharmacol, 2004, 493(1-3), 85-93.
- [1]. Pullar IA, et al. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur J Pharmacol, 2004, 493(1-3), 85-93.
- [2]. Choi IS, et al. 5-HT(1B) receptors inhibit glutamate release from primary afferent terminals in rat medullary dorsal horn neurons. Br J Pharmacol, 2012,167(2), 356-367.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
