Eslicarbazepine acetate 醋酸艾司利卡西平
CAS 236395-14-5 MFCD06798333
化学结构图
SMILES: CC(=O)O[C@H]1CC2C=CC=CC=2N(C(N)=O)C2C=CC=CC=21
化学属性
| Mol. Formula | C17H16N2O3 |
|---|---|
| Mol. Weight | 296.33 |
| Melting Point | 185.0 to 189.0 deg-C |
别名和识别编码
| Chemical Name | Eslicarbazepine acetate |
|---|---|
| CAS Number | 236395-14-5 |
| Synonym | (10S)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide BIA 2-093 S-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide Sep 0002093 |
| PubChem Substance ID | 253662249 |
| MDL Number | MFCD06798333 |
| Reaxys-RN | 8336447 |
| Chemical Name Translation | 醋酸艾司利卡西平 |
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分类
- B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels
- {SNA} B, Bioactive Small Molecule Alphabetical Index, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Monovalent I
产品应用
- Eslicarbazepine acetate, (BIA 2-093), is a promising antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.
相关文献及参考
- Benes, J., et al.: J. Med. Chem., 42, 2582 (1999),
- Parada, A., and Soares-da-Silva, P., The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine. Neurochem. Int. 40 , 435-440, (2002) 摘要
- Bonifacio, M.J., et al., Interaction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine. Epilepsia 42 , 600-608, (2001) 摘要
- Merck 14 ,10416
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
- P304+P340+P312
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P405 Store locked up. 上锁保管。
- P305+P351+P338
- P403+P233
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
