5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol 2-羟基吡啶-5-硼酸频哪醇酯

CAS 1054483-78-1 MFCD06795671

化学结构图

1054483-78-1
SMILES: CC1(C)OB(OC1(C)C)C1C=NC(O)=CC=1

化学属性

Mol. FormulaC11
Mol. Weight221
Melting Point196-200 °C
TSCANo

别名和识别编码

Chemical Name5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol
CAS Number1054483-78-1
Synonym 2-羟基-5-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)吡啶 2-羟基吡啶-5-硼酸频那醇酯 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 6-羟基吡啶-3-硼酸频那醇酯 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-pyridinone
MDL NumberMFCD06795671
Chemical Name Translation2-羟基吡啶-5-硼酸频哪醇酯
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分类

  • Heterocycles
  • Pharmaceuticals
  • Boron Derivatives
  • {SNA} Boronate Esters, Boronic Acids and Derivatives, Chemical Synthesis, Heteroaryl Boronate Esters, Organometallic Reagents
  • Intermediates & Fine Chemicals
  • Aromatics

产品应用

  • 6-Hydroxypyridine-3-boronic Acid Pinacol ester is used in the preparation of modified C3 Betulinic acid (B330250) derivatives as HIV maturation inhibitors.

相关文献及参考

  • Ma, C., et al.: Chem. Pharm. Bull., 48, 1681 (2000),
  • Zhu, Y., et al.: Bioorg. Med. Chem. Lett., 11, 3115 (2001),

安全信息

GHS Symbol
WGK Germany2
Precautionary statements
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R38 Irritating to skin 刺激皮肤
  • R36 Irritating to eyes 刺激眼睛

系列性分类


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