CAS 477-73-6 MFCD00011759-Safranine T 藏红T TAO{mole}

Safranine T 藏红T

CAS 477-73-6 MFCD00011759

化学结构图

SMILES: Cc1cc2nc3cc(C)c(N)cc3[n+](-c3ccccc3)c2cc1N.[Cl-]

化学属性

Mol. Formula	C20H19ClN4
Mol. Weight	350.84
Density	0.986 g/mL at 20 °C
Refractive index	n20/D 1.339
TSCA	Yes
Solubility	Soluble in water (50 mg/ml at 20 °C), and alcohol.
Stability	对湿度敏感
Flash Point	46 °C
Melting Point	>240 °C
Boiling Point	507.14 °C at 760 mmHg

别名和识别编码

Chemical Name	Safranine T
Synonym	Safranin {LY} Safranin {} {LY} Safranin {} {} {LY} Safranin {} {} {} {LY} Safranin {} {} {} {} {LY} Safranin {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Safranin {} {} {} {} {} {} {
MDL Number	MFCD00011759
Beilstein Registry Number	3924099
CAS Number	477-73-6
EC Number	207-518-8
Reaxys-RN	3924099
PubChem Substance ID	2723800
Chemical Name Translation	藏红T
InChIKey	OARRHUQTFTUEOS-UHFFFAOYSA-N
LabNetwork Molecule ID	LN00195469
InChI	InChI=1S/C20H18N4.ClH/c1-12-8-17-19(10-15(12)21)24(14-6-4-3-5-7-14)20-11-16(22)13(2)9-18(20)23-17;/h3-11H,1-2H3,(H3,21,22);1H
Canonical SMILES	CC1=CC2=NC3=C([N+](C4=CC=CC=C4)=C2C=C1N)C=C(N)C(C)=C3.[Cl-]

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产品应用

微量分析亚硝酸的试剂。氧化还原指示剂、酸碱指示剂、生物染色剂。
高纯级用在Flemming triple染色中的染色体染色；在吉姆萨染色中对革兰氏阴性细菌染色；在Safranine-fast green FCF染色中对植物细胞染色。

安全信息

GHS Symbol

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H315 Causes skin irritation 会刺激皮肤
H318 Causes serious eye damage 严重伤害眼睛
H319 Causes serious eye irritation 严重刺激眼睛

WGK Germany3

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Gloves Eyeshields, Gloves

Signal word Danger Warning

RTECSSG1623000

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P302+P352
P302+P352+P332+P313+P362+P364
P305+P351+
P305+P351+P338
P305+P351+P338+P337+P313
P308+P313
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P332+P313
P337+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R10 Flammable 易燃
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险

Hazard Codes F Xi

Storage condition RT, sealed storage, away from moisture and light {LY} RT, sealed storage, away from moisture and light Store at RT. {} {LY} RT, sealed storage, away from moisture and light {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed stor

UN Number UN 1170 3/PG 3

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 26940 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   SMBUA9 Stanford Medical Bulletin.  (Palo Alto, CA)  V.1-20, 1942-62.
   Discontinued.  Volume(issue)/page/year: 9,96,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28740 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   SMBUA9 Stanford Medical Bulletin.  (Palo Alto, CA)  V.1-20, 1942-62.
   Discontinued.  Volume(issue)/page/year: 9,96,1951

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 69,327,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24020 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   SMBUA9 Stanford Medical Bulletin.  (Palo Alto, CA)  V.1-20, 1942-62.
   Di

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 2 mg/disc
REFERENCE :
   TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho.  Annual Report of Tokyo
   Metropolitan Research Laboratory of Public Health.  (Tokyo-toritsu Eisei
   Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1-
      1949/50-  Volume(issue)/page/year: 27,153,1976

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 16 ug/plate
REFERENCE :
   TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho.  Annual Report of Tokyo
   Metropolitan Research Laboratory of Public Health.  (Tokyo-toritsu Eisei
   Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1-
      1949/50-  Volume(issue)/page/year: 27,153,1976

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 4 ug/well
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,429,1981

其他信息

稳定性:Stable.
用途:用作微量分析亚硝酸的试剂、氧化还原指示剂、酸碱指示剂、生物染色剂
MOL 文件:477-73-6.mol
色指数:50240
图谱信息:碱性红 2(477-73-6)红外图谱(IR1) 碱性红 2(477-73-6)红外图谱(IR2)
毒害物质数据:477-73-6(Hazardous Substances Data)
碱性红 2价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 71037844 藏红T;碱性藏红花;番红花红T;蓝光藏红花;盐基桃红;沙黄 25g 44.5元 2011/04/16 S0145 碱性红2 Basic Red 2 25G 383元 2011/04/16 S0145 碱性红2 Basic Red 2 500G 3640元
EPA化学物质信息:Phenazinium, 3,7-diamino-2,8-dimethyl-5- phenyl-, chloride(477-73-6)
易溶于水成红色溶液，溶于乙醇成红色带黄红色荧光。对盐酸为蓝红色溶液，过多则呈紫色，大量过多则转为蓝色；对氢氧化钠则生成桲红色沉淀；硫酸则为绿色溶液，稀释时先变成蓝色，渐变成紫色，最后变为红色。最大吸收波长530nm。有刺激性。商品中常混杂有甲基藏红T。Colour Index Number 50240
易溶于水成红色溶液，溶于乙醇成红色带黄红色荧光。对盐酸为蓝红色溶液，过多则呈紫色，大量过多则转为蓝色；对氢氧化钠则生成桲红色沉淀；硫酸则为绿色溶液，稀释时先变成蓝色，渐变成紫色，最后变为红色。最大吸收波长530nm。有刺激性。商品中常混杂有甲基藏红T。
海关编码:32041300
生产方法:以 2，5-二氨基甲苯、邻甲苯胺和苯胺为原料，首先将等摩尔的 2，5-二氨基甲苯与邻甲苯胺氧化，然后与苯胺缩合，通过精制结晶，转变成氯化物而得成品。
RTECS号:SG1623000