1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1) 羟基法舒地尔单盐酸盐
CAS 155558-32-0 MFCD06411567
化学结构图
SMILES:
化学属性
| Mol. Formula | C14H18ClN3O3S |
|---|---|
| Mol. Weight | 344 |
别名和识别编码
| Chemical Name | 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1) |
|---|---|
| Synonym | 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate |
| MDL Number | MFCD06411567 |
| PubChem Substance ID | 24724499 |
| CAS Number | 155558-32-0 |
| Chemical Name Translation | 羟基法舒地尔单盐酸盐 |
| LabNetwork Molecule ID | LN01284983 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase Biology, R to Z,
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, H, Kinase/Phosphatase Biology, R to Z, Rho Kinase (ROCK), Rho-Kinase, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学,
相关文献及参考
- [2]. Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladder overactivity: an experimental rat model. Int J Urol. 2009 Oct;16(10):842-7.
- [3]. Saito M, et al. Hydroxyfasudil ameliorates penile dysfunction in the male spontaneously hypertensive rat. Pharmacol Res. 2012 Oct;66(4):325-31.
- Nakamura, K., et al. , Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase. J. Cereb. Blood Flow Metab. 21 , 876-885, (2001) 摘要
- [1]. Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1.
- [1]. Rikitake Y, et al. Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005 Oct;36(10):2251-7. Epub 2005 Sep 1.
- [2]. Masago T, et al. Effect of the rho-kinase inhibitor hydroxyfasudil on bladde
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
