GW311616A
CAS 197090-44-1 MFCD06411566
化学结构图
SMILES: Cl.CC(C)[C@H]1[C@H]2[C@@H](CCN2C(=O)/C=C/CN2CCCCC2)N(C1=O)S(C)(=O)=O
化学属性
| Mol. Formula | C19H32ClN3O4S |
|---|---|
| Mol. Weight | 433.99 |
别名和识别编码
| Chemical Name | GW311616A |
|---|---|
| Synonym | (3S,3aS,6aR)-3-Isopropyl-1-(methanesulfonyl)-4-[4-(1-piperidinyl)-2(E)-butenoyl]perhydropyrrolo[3,2b]pyrrol-2(1H)-one hydrochloride |
| MDL Number | MFCD06411566 |
| CAS Number | 197090-44-1 |
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资金保障
专业采购外包团队在线服务
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分类
- Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, D to K, Elastase, neutrophil, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Enzymes, Substrates, Inhibitors &, Modulators for Stem Cell Biology, G, General Stem Cell Biology, GlaxoSmithKline, Inhibitors, Stem Cell Biology, Stem Cell Characterization
- {SA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, D to K,
相关文献及参考
- Macdonald, S.J., et al., The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase−GW311616A a development candidate. Bioorg. Med. Chem. Lett. 11 , 895-898, (2001)
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
