20(S)-Ginsenoside Rg3 人参皂甙Rg3
CAS 14197-60-5 MFCD06410950
化学结构图
SMILES: CC1(C)[C@@H]2CC[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@@](C)(O)CCC=C(C)C)[C@@]2(C)CC[C@@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
化学属性
| Mol. Formula | C42H72O13 |
|---|---|
| Mol. Weight | 785 |
| Melting Point | 209-219 |
| Density | 1.30 |
别名和识别编码
| Chemical Name | 20(S)-Ginsenoside Rg3 |
|---|---|
| Synonym | (20S)-Propanaxadiol |
| CAS Number | 14197-60-5 |
| MDL Number | N/A |
| Chemical Name Translation | 人参皂甙Rg3 |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Alphabetical, Analytical Standards, Analytical/Chromatography, Chromatography, E - H, Isoprenoids, Life Sciences Standards, Nutrition Research, Panax, Panax ginseng, Phytochemicals by Plant (Food/Spice/Herb), Phytopharma Standards, Standards by Plant Genus, Substance Classification
- {SNA} Bioactive Small Molecule Alphabetical Index, G, Ion Channels, Monovalent Ion Channels, Phytochemicals by Chemical Classification, Potassium Channel Modulators, Saponins, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学,
相关文献及参考
- [2]. Lee JH, et al. Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue. Mol Pharmacol. 2008 Mar;73(3):619-26.
- [3]. Lee IS, et al. Anti-Inflammatory Effects of Ginsenoside Rg3 via NF-κB Pathway in A549 Cells and Human Asthmatic Lung Tissue. J Immunol Res. 2016;2016:7521601.
- [4]. Kang MS, et al. Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. J Biol Chem. 2013 Jul 19;288(29):20868-82.
- [1]. Kim JH, et al. A role for the carbohydrate portion of ginsenoside Rg3 in Na + channel inhibition. Mol Cells. 2005 Feb 28;19(1):137-42.
- [1]. Kim JH, et al. A role for the carbohydrate portion of ginsenoside Rg3 in Na + channel inhibition. Mol Cells. 2005 Feb 28;19(1):137-42.
- [2]. Lee JH, et al. Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue. Mol Pharmacol. 2008 Mar;7
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,343,1975
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P301+P312
- P330 Rinse mouth. 漱口
