CAS 104987-12-4 MFCD06198665-Ascomycin 长川霉素 TAO{mole}

Ascomycin 长川霉素

CAS 104987-12-4 MFCD06198665

化学结构图

SMILES: CC[C@@H]1C=C(C)C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)/C(/C)=C/[C@H]1C[C@@H](OC)[C@H](O)CC1 |c:3|

化学属性

Mol. Formula	C43H69NO12
Mol. Weight	792
Melting Point	160-161

别名和识别编码

Chemical Name	Ascomycin
CAS Number	104987-12-4
Synonym	FR 900520 FR 520 Ascomycin L 683590 Immunomycin FK 520 Changchuanmycin
MDL Number	MFCD06198665
PubChem Substance ID	24890817
Beilstein Registry Number	5372600
Chemical Name Translation	长川霉素

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分类

{SNA}
{SNA} AN-AZ, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Bioactive Small Molecule Alphabetical Index, Chemical Structure Class, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Kinase/Phosphatase Biology, Macrolactams, Protein Phosphatase 2B (Calcineurin/PP2B), Serine/Threonine Kinase Biology, Serine/Threonine Phosphatase Inhibitors, Spectrum of Activity, 抗生素, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
AN-AZ, Antibiotics, Antibiotics A to Z,

产品应用

A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases.

安全信息

RTECSKD4185000

WGK Germany3

GHS Symbol

Precautionary statements

Signal word

Hazard statements

H332 Harmful if inhaled 吸入有害
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害

Hazard Codes Xn

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Risk Statements

R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1592,1988