URB597
CAS 546141-08-6 MFCD05863934
化学结构图
SMILES: NC(=O)C1C=C(C=CC=1)C1C=C(C=CC=1)OC(=O)NC1CCCCC1
化学属性
| Mol. Formula | C20H22N2O3 |
|---|---|
| Mol. Weight | 338.40 |
别名和识别编码
| Chemical Name | URB597 |
|---|---|
| CAS Number | 546141-08-6 |
| Alfabeta Name | CARBAMOYLBIPHENYLYLCYCLOHEXYLCARBAMATE 3113[]-----,'' |
| MDL Number | MFCD05863934 |
| Synonym | Cyclohexylcarbamic acid 3´-carbamoyl-biphenyl-3-yl ester |
| PubChem Substance ID | 329827629 |
| Chemical Name Translation |
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分类
- {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Fatty Acid Amide Hydrolase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, U
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Fatty Acid Amide Hydrolase, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, U, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- Niforatos W., et al, Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597). Mol. Pharmacol. 71 , 1209-16, (2007) 摘要
- Murillo-Rodriguez E., et al, Effects of the fatty acid amide hydrolase inhibitor URB597 on the sleep-wake cycle, c-Fos expression and dopamine levels of the rat. Eur. J. Pharmacol. 562 , 82-91, (2007) 摘要
- Russo R., et al, The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J. Pharmacol. Exp. Ther. 322 , 236-42, (2007) 摘要
安全信息
GHS Symbol
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P273 Avoid release to the environment. 避免释放到环境中。
- P305+P351+P338
- H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
- H319 Causes serious eye irritation 严重刺激眼睛
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S22 Do not breathe dust 不要吸入粉尘；
- R50/53
