Ginkgolide B 银杏内酯 B
CAS 15291-77-7 MFCD05662347
化学结构图
SMILES: CC(C)(C)[C@@H]1C[C@H]2OC(=O)[C@@]34O[C@@H]5OC(=O)[C@H](O)[C@]51[C@]32[C@@H](O)[C@@H]1OC(=O)[C@@H](C)[C@]41O
化学属性
| Mol. Formula | C20H24O10 |
|---|---|
| Mol. Weight | 424.40 |
| TSCA | No |
| Melting Point | >300 |
别名和识别编码
| Chemical Name | Ginkgolide B |
|---|---|
| CAS Number | 15291-77-7 |
| Synonym | 银杏内酯 B (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,1 银杏内酯 B 来源于银杏 叶 BN-52021 |
| MDL Number | MFCD05662347 |
| PubChem Substance ID | 24895280 |
| Beilstein Registry Number | 4727611 |
| Merck Number | 14,4426 |
| Chemical Name Translation | 银杏内酯 B |
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分类
- {SNA} Analytical Standards, Antioxidant and Free Radical Scavengers, Asymmetric Synthesis, Chemical Synthesis, Chemopreventive Agents, Chiral Building Blocks, Complex Molecules, Isoprenoids, Phytochemical Standards, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids), 分析/色谱, 癌症研究, 细胞生物学, 营养研究
- {SNA} Analytical Standards,
- {SNA} Alphabetical, Analytical Standards, Analytical/Chromatography, Chromatography, E - H, Ginkgo, Ginkgo biloba, Isoprenoids, Life Sciences Standards, Natural Compounds,
- Pharmaceuticals
- {SN
产品应用
- Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.
相关文献及参考
- [2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302
- Braquet, P., et al.: Med. Res. Rev., 11, 295 (1991),
- Korth, R., et al.: Eur. J. Pharmacol., 152, 101 (1988),
- [1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43
- [1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43
- [2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302
安全信息
GHS Symbol
