Quercetin 3-Glucuronide 槲皮素-3-葡萄糖醛酸苷
CAS 22688-79-5 MFCD04039814
化学结构图
SMILES: OC(=O)[C@H]1OC(OC2=C(OC3C=C(O)C=C(O)C=3C2=O)C2C=C(O)C(O)=CC=2)[C@H](O)[C@@H](O)[C@@H]1O
化学属性
| Mol. Formula | C21H18O13 |
|---|---|
| Mol. Weight | 478 |
| Density | 1.422 |
别名和识别编码
| Chemical Name | Quercetin 3-Glucuronide |
|---|---|
| CAS Number | 22688-79-5 |
| Synonym | 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl β-D-Glucopyranosiduronic Acid, Mikwelianin |
| EC Number | 250-023-7 |
| Beilstein Registry Number | 2384789 |
| Chemical Name Translation | 槲皮素-3-葡萄糖醛酸苷 |
| MDL Number | MFCD04039814 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Heterocycles
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Tyrosine Kinase Inhibitors
产品应用
- Quercetin 3-O-?-D-Glucuronide is the major metabolite of Quercetin (Q509500).
相关文献及参考
- [2]. Juergenliemk G, et al. In vitro studies indicate that miquelianin (quercetin 3-O-beta-D-glucuronopyranoside) is able to reach the CNS from the small intestine. Planta Med. 2003 Nov;69(11):1013-7.
- [3]. Butterweck V, et al. Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Med. 2000 Feb;66(1):3-6.
- [4]. Yamazaki S, et al. Quercetin-3-O-glucuronide inhibits noradrenaline-promoted invasion of MDA-MB-231 human breast cancer cells by blocking β-adrenergic signaling. Arch Biochem Biophys. 2014 Sep 1;557:18-27.
- [5]. Ho L, et al. Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease. FASEB J. 2013 Feb;27(2):769-81.
- Ajay, M., et al.: Life Sci., 74, 603 (2003),
- Amira, S., et al.: Eur. J. Pharmacol. 599, 126 (2008),
- Shen, S., et al.: Toxicol. Appl. Pharmacol., 197, 84 (2004),
- [1]. Terao J, e al. Protection
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
