SKF-83959 hydrobromide
CAS 80751-85-5 MFCD03792727
化学结构图
SMILES: Br.CC1C=CC=C(C=1)C1CN(C)CCC2=C(Cl)C(O)=C(O)C=C21
化学属性
| Mol. Formula | C18H20NClO2· HBr |
|---|---|
| Mol. Weight | 398.72 |
别名和识别编码
| Chemical Name | SKF-83959 hydrobromide |
|---|---|
| Synonym | 6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide SKF-83959 hydrobromide |
| MDL Number | MFCD03792727 |
| PubChem Substance ID | 24278699 |
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分类
- {SNA} Agonists, Bioactive Small Molecule Alphabetical Index, Dopaminergics, Dopaminergics - Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, S, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- {SNA} Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics, Dopaminergics - Agonists, GPCR Modulators, GPCR Protei
相关文献及参考
- [2]. Jin LQ, et al. SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain. J Neurochem. 2003;85(2):378-386.
- [3]. Neumeyer JL, et al. Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. Eur J Pharmacol. 2003;474(2-3):137-140.
- [4]. Guo L, et al. SKF83959 is a potent allosteric modulator of sigma-1 receptor. Mol Pharmacol. 2013;83(3):577-586.
- [1]. Sheng G, et al. SKF83959 Has Protective Effects in the Scopolamine Model of Dementia. Biol Pharm Bull. 2018;41(3):427-434.
- [1]. Sheng G, et al. SKF83959 Has Protective Effects in the Scopolamine Model of Dementia. Biol Pharm Bull. 2018;41(3):427-434.
- [2]. Jin LQ, et al. SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain. J Neurochem. 2003;85(2):378-386.
- [3]. Neumeyer JL, et al. Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. Eur J Pharmacol. 2
