3-[3-[2,5-DIHYDRO-4-(1-METHYL-1H-INDOL-3-YL)-2,5-DIOXO-1H-PYRROL-3-YL]-1H-INDOL-1-YL]PROPYL CARBAMIMIDOTHIOIC ACID ESTER MESYLATE
CAS 125314-64-9 MFCD03788207
化学结构图
SMILES: CN1C=C(C2=C(C3=CN(CCCSC(N)=N)C4C=CC=CC=43)C(=O)NC2=O)C2C=CC=CC1=2.CS(O)(=O)=O
化学属性
| Mol. Formula | C25H23N5O2S · CH3SO3H |
|---|---|
| Mol. Weight | 553.65 |
别名和识别编码
| Chemical Name | Ro 31-8220 methanesulfonate salt |
|---|---|
| Synonym | 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate salt Bisindoylmaleimidine IX |
| MDL Number | MFCD03788207 |
| PubChem Substance ID | 329824000 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates,
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Kinase/Phosphatase Biology, L to O, MAPKAP kinase-1beta and p70 S6 kinase, Protein Kinase Inhibitors, Protein kinase C, G-protein coupled receptor kinase, MAPK-activated protein kinase (PKC, GRK, MAPKAP Kinase), R, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
相关文献及参考
- Moore, J.B., et al., Inhibition of PTH desensitization by inhibition of the G protein-coupled receptor kinase-5 enzyme with Ro 32-0432. FASEB J. 12 , A741, (1998)
- Beltman, J., et al., The selective protein kinase C inhibitor Ro-31-8220 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression induces c-Jun expression and activates J N-terminal kinase. J. Biol. Chem. 271 , 27018, (1996) 摘要
- Alessi, D.R., The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase –1β (Rsk-2) and p70 S6 kinase. FEBS Lett. 402 , 121-123, (1997) 摘要
