1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID, N-HEPTYL ESTER
CAS N/A MFCD03412025
化学结构图
SMILES: CC1=C(CC(=O)OCCCCCCC)C2C=C(C=CC=2N1C(=O)C1C=CC(Cl)=CC=1)OC
化学属性
| Mol. Formula | C26H30ClNO4 |
|---|---|
| Mol. Weight | 455.97 |
别名和识别编码
| Chemical Name | Indomethacin heptyl ester |
|---|---|
| MDL Number | MFCD03412025 |
| Synonym | |
| EC Number | 201-185-2 |
| PubChem Substance ID | 329815317 |
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资金保障
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分类
- {SNA} A to C,
- {SNA} A to C, Application Index, Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research,
- {SA} A to C, Application Index, Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research,
相关文献及参考
- Barnett, J., et al., Purification, characterization, and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in baculovirus system. Biochim. Biophys. Acta 1209 , 130, (1994) 摘要
- Kalgutkar, A.S., Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. J. Med. Chem. 43 , 2860, (2000) 摘要
安全信息
GHS Symbol
- R11 Highly flammable 非常易燃
- R36 Irritating to eyes 刺激眼睛
- R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
- R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
- S33 Take precautionary measures against static discharges 对静电采取预防措施；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S29 Do not empty into drains 不要排入下水道；
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- P304+P340+P312
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P337+P313
- P403+P235
