Trans-4-Methylene-2-Octyl-5-Oxotetrahydrofuran-3-Carboxylic Acid 反式-4-亚甲基-2-辛基-5-氧代四氢呋喃-3-羧酸
CAS 191282-48-1 MFCD91282481
化学结构图
SMILES: C=C1C(=O)OC(CCCCCCCC)C1C(=O)O
化学属性
| Mol. Weight | 254.3221 |
|---|---|
| Mol. Formula | C14H22O4 |
别名和识别编码
| CAS Number | 191282-48-1 |
|---|---|
| Chemical Name | Trans-4-Methylene-2-Octyl-5-Oxotetrahydrofuran-3-Carboxylic Acid |
| Synonym | (2R,3S)-rel-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid 4-methylene-2-octyl-5-oxofuran-3-carboxylic acid C 75 C75 cpd trans-4-carboxy-5-octyl-3-methylenebutyrolactone trans-C 75 |
| Chemical Name Translation | 反式-4-亚甲基-2-辛基-5-氧代四氢呋喃-3-羧酸 |
| LabNetwork Molecule ID | LN00194653 |
| PubChem Substance ID | 9881506 |
| InChI | InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)/t11-,12+/m1/s1 |
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分类
- Heterocycles
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
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相关文献及参考
- [2]. Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity. Chirality. 2013 May;25(5):281-7.
- [3]. Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33.
- [4]. Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.
- Rae, C. et al.: DIab. Obes. Metab., 10, 1271 (2008); Gao, Y. et al.: Cancer Biol. Ther., 5, 978 (2006); Flavin, R. et al.: Fut. Oncol., 6, 551 (2010);
- [1]. Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy.
- [1]. Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy.
- [2]. Makowski K, et al. Differen
