(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester ((5Z,8Z,11Z,14Z)-二十碳-5,8,11,14-四烯-1-基)氟磷酸甲酯

CAS 188404-10-6 MFCD03095722

化学结构图

188404-10-6
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC

化学属性

Mol. FormulaC21H36FO2P
Mol. Weight370.48

别名和识别编码

Chemical Name(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester
Synonym MAPF MAPF Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester
EC Number201-185-2
MDL NumberMFCD03095722
CAS Number188404-10-6
Chemical Name Translation((5Z,8Z,11Z,14Z)-二十碳-5,8,11,14-四烯-1-基)氟磷酸甲酯
PubChem Substance ID329817956
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分类

  • {SNA} Analytical and Industrial Enzymes, Bioactive Small Molecule Alphabetical Index, Cholinesterase Inhibitors, Cholinesterase and Organophosphate Detection Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Lipids in Cell Signaling, M, P to Q, Phospholipase A2, Phospholipase Inhibitors, Phospholipid Metabolism, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors,

相关文献及参考

  • Balsinde, J., Dennis, E.A., Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages. J. Biol. Chem. 271 , 6758, (1996) 摘要
  • Lio, Y-C., Irreversible inhibition of Ca +2 -independent phospholipase A2 by methyl arachidonyl fluorophosphonate. Biochim. Biophys. Acta 1302 , 55, (1996) 摘要

安全信息

GHS Symbol
WGK Germany2
Hazard Codes F,Xi
Hazard statements
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P304+P340+P312
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P337+P313
  • P403+P235
Signal word Danger
Risk Statements
  • R11 Highly flammable 非常易燃
  • R36 Irritating to eyes 刺激眼睛
  • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
  • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
Safety Statements
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S29 Do not empty into drains 不要排入下水道；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Halogenated 卤化物 (氟氯溴碘)
  5. Fluoro 氟化物
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. P to Q - Enzyme Inhibitors by Enzyme
  7. Phospholipase A2 - P to Q
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Lipids in Cell Signaling - Cell Signaling and Neuroscience
  5. Phospholipid Metabolism - Lipids in Cell Signaling
  6. Phospholipase Inhibitors - Phospholipid Metabolism

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